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Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure.
Meissner A, Yang J, Kroetsch JT, Sauvé M, Dax H, Momen A, Noyan-Ashraf MH, Heximer S, Husain M, Lidington D, Bolz SS. Meissner A, et al. Circulation. 2012 Jun 5;125(22):2739-50. doi: 10.1161/CIRCULATIONAHA.111.047316. Epub 2012 Apr 25. Circulation. 2012. PMID: 22534621
Proximal cerebral arteries develop myogenic responsiveness in heart failure via tumor necrosis factor-α-dependent activation of sphingosine-1-phosphate signaling.
Yang J, Noyan-Ashraf MH, Meissner A, Voigtlaender-Bolz J, Kroetsch JT, Foltz W, Jaffray D, Kapoor A, Momen A, Heximer SP, Zhang H, van Eede M, Henkelman RM, Matthews SG, Lidington D, Husain M, Bolz SS. Yang J, et al. Among authors: meissner a. Circulation. 2012 Jul 10;126(2):196-206. doi: 10.1161/CIRCULATIONAHA.111.039644. Epub 2012 Jun 5. Circulation. 2012. PMID: 22668972
CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage.
Lidington D, Fares JC, Uhl FE, Dinh DD, Kroetsch JT, Sauvé M, Malik FA, Matthes F, Vanherle L, Adel A, Momen A, Zhang H, Aschar-Sobbi R, Foltz WD, Wan H, Sumiyoshi M, Macdonald RL, Husain M, Backx PH, Heximer SP, Meissner A, Bolz SS. Lidington D, et al. Among authors: meissner a. JACC Basic Transl Sci. 2019 Nov 27;4(8):940-958. doi: 10.1016/j.jacbts.2019.07.004. eCollection 2019 Dec. JACC Basic Transl Sci. 2019. PMID: 31909302 Free PMC article.
591 results