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Page 1
The gut microbial metabolite formate exacerbates colorectal cancer progression.
Ternes D, Tsenkova M, Pozdeev VI, Meyers M, Koncina E, Atatri S, Schmitz M, Karta J, Schmoetten M, Heinken A, Rodriguez F, Delbrouck C, Gaigneaux A, Ginolhac A, Nguyen TTD, Grandmougin L, Frachet-Bour A, Martin-Gallausiaux C, Pacheco M, Neuberger-Castillo L, Miranda P, Zuegel N, Ferrand JY, Gantenbein M, Sauter T, Slade DJ, Thiele I, Meiser J, Haan S, Wilmes P, Letellier E. Ternes D, et al. Among authors: meiser j. Nat Metab. 2022 Apr;4(4):458-475. doi: 10.1038/s42255-022-00558-0. Epub 2022 Apr 18. Nat Metab. 2022. PMID: 35437333 Free PMC article.
Increased formate overflow is a hallmark of oxidative cancer.
Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton JP, Dornier E, Sumpton D, Mackay GM, Blyth K, Patel KJ, Niclou SP, Vazquez A. Meiser J, et al. Nat Commun. 2018 Apr 10;9(1):1368. doi: 10.1038/s41467-018-03777-w. Nat Commun. 2018. PMID: 29636461 Free PMC article.
Formate metabolism in health and disease.
Pietzke M, Meiser J, Vazquez A. Pietzke M, et al. Among authors: meiser j. Mol Metab. 2020 Mar;33:23-37. doi: 10.1016/j.molmet.2019.05.012. Epub 2019 Jul 30. Mol Metab. 2020. PMID: 31402327 Free PMC article. Review.
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis.
Kiweler N, Delbrouck C, Pozdeev VI, Neises L, Soriano-Baguet L, Eiden K, Xian F, Benzarti M, Haase L, Koncina E, Schmoetten M, Jaeger C, Noman MZ, Vazquez A, Janji B, Dittmar G, Brenner D, Letellier E, Meiser J. Kiweler N, et al. Among authors: meiser j. Nat Commun. 2022 May 16;13(1):2699. doi: 10.1038/s41467-022-30363-y. Nat Commun. 2022. PMID: 35577770 Free PMC article.
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing.
Danileviciute E, Zeng N, Capelle CM, Paczia N, Gillespie MA, Kurniawan H, Benzarti M, Merz MP, Coowar D, Fritah S, Vogt Weisenhorn DM, Gomez Giro G, Grusdat M, Baron A, Guerin C, Franchina DG, Léonard C, Domingues O, Delhalle S, Wurst W, Turner JD, Schwamborn JC, Meiser J, Krüger R, Ranish J, Brenner D, Linster CL, Balling R, Ollert M, Hefeng FQ. Danileviciute E, et al. Among authors: meiser j. Nat Metab. 2022 May;4(5):589-607. doi: 10.1038/s42255-022-00576-y. Epub 2022 May 26. Nat Metab. 2022. PMID: 35618940
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.
Green AC, Marttila P, Kiweler N, Chalkiadaki C, Wiita E, Cookson V, Lesur A, Eiden K, Bernardin F, Vallin KSA, Borhade S, Long M, Ghahe EK, Jiménez-Alonso JJ, Jemth AS, Loseva O, Mortusewicz O, Meyers M, Viry E, Johansson AI, Hodek O, Homan E, Bonagas N, Ramos L, Sandberg L, Frödin M, Moussay E, Slipicevic A, Letellier E, Paggetti J, Sørensen CS, Helleday T, Henriksson M, Meiser J. Green AC, et al. Among authors: meiser j. Nat Metab. 2023 Apr;5(4):642-659. doi: 10.1038/s42255-023-00771-5. Epub 2023 Apr 3. Nat Metab. 2023. PMID: 37012496 Free PMC article.
IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer.
Koncina E, Nurmik M, Pozdeev VI, Gilson C, Tsenkova M, Begaj R, Stang S, Gaigneaux A, Weindorfer C, Rodriguez F, Schmoetten M, Klein E, Karta J, Atanasova VS, Grzyb K, Ullmann P, Halder R, Hengstschläger M, Graas J, Augendre V, Karapetyan YE, Kerger L, Zuegel N, Skupin A, Haan S, Meiser J, Dolznig H, Letellier E. Koncina E, et al. Among authors: meiser j. Nat Commun. 2023 Jul 17;14(1):4251. doi: 10.1038/s41467-023-39953-w. Nat Commun. 2023. PMID: 37460545 Free PMC article.
Formate promotes invasion and metastasis in reliance on lipid metabolism.
Delbrouck C, Kiweler N, Chen O, Pozdeev VI, Haase L, Neises L, Oudin A, Fouquier d'Hérouël A, Shen R, Schlicker L, Halder R, Lesur A, Schuster A, Lorenz NI, Jaeger C, Feucherolles M, Frache G, Szpakowska M, Chevigne A, Ronellenfitsch MW, Moussay E, Piraud M, Skupin A, Schulze A, Niclou SP, Letellier E, Meiser J. Delbrouck C, et al. Among authors: meiser j. Cell Rep. 2023 Sep 26;42(9):113034. doi: 10.1016/j.celrep.2023.113034. Epub 2023 Aug 30. Cell Rep. 2023. PMID: 37651228 Free article.
Author Correction: The gut microbial metabolite formate exacerbates colorectal cancer progression.
Ternes D, Tsenkova M, Pozdeev VI, Meyers M, Koncina E, Atatri S, Schmitz M, Karta J, Schmoetten M, Heinken A, Rodriguez F, Delbrouck C, Gaigneaux A, Ginolhac A, Nguyen TTD, Grandmougin L, Frachet-Bour A, Martin-Gallausiaux C, Pacheco M, Neuberger-Castillo L, Miranda P, Zuegel N, Ferrand JY, Gantenbein M, Sauter T, Slade DJ, Thiele I, Meiser J, Haan S, Wilmes P, Letellier E. Ternes D, et al. Among authors: meiser j. Nat Metab. 2023 Sep;5(9):1638. doi: 10.1038/s42255-023-00898-5. Nat Metab. 2023. PMID: 37709964 Free PMC article. No abstract available.
69 results