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Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: meikle pj. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Lipidomic Profiles in Diabetes and Dementia.
Huynh K, Martins RN, Meikle PJ. Huynh K, et al. Among authors: meikle pj. J Alzheimers Dis. 2017;59(2):433-444. doi: 10.3233/JAD-161215. J Alzheimers Dis. 2017. PMID: 28582856 Review.
MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.
Burla B, Arita M, Arita M, Bendt AK, Cazenave-Gassiot A, Dennis EA, Ekroos K, Han X, Ikeda K, Liebisch G, Lin MK, Loh TP, Meikle PJ, Orešič M, Quehenberger O, Shevchenko A, Torta F, Wakelam MJO, Wheelock CE, Wenk MR. Burla B, et al. Among authors: meikle pj. J Lipid Res. 2018 Oct;59(10):2001-2017. doi: 10.1194/jlr.S087163. Epub 2018 Aug 16. J Lipid Res. 2018. PMID: 30115755 Free PMC article.
Lipidomics Reveals a Tissue-Specific Fingerprint.
Pradas I, Huynh K, Cabré R, Ayala V, Meikle PJ, Jové M, Pamplona R. Pradas I, et al. Among authors: meikle pj. Front Physiol. 2018 Aug 28;9:1165. doi: 10.3389/fphys.2018.01165. eCollection 2018. Front Physiol. 2018. PMID: 30210358 Free PMC article.
Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology.
Barupal DK, Baillie R, Fan S, Saykin AJ, Meikle PJ, Arnold M, Nho K, Fiehn O, Kaddurah-Daouk R; Alzheimer Disease Metabolomics Consortium. Barupal DK, et al. Among authors: meikle pj. Alzheimers Dement (Amst). 2019 Sep 5;11:619-627. doi: 10.1016/j.dadm.2019.07.002. eCollection 2019 Dec. Alzheimers Dement (Amst). 2019. PMID: 31517024 Free PMC article.
Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome.
Arnold M, Nho K, Kueider-Paisley A, Massaro T, Huynh K, Brauner B, MahmoudianDehkordi S, Louie G, Moseley MA, Thompson JW, John-Williams LS, Tenenbaum JD, Blach C, Chang R, Brinton RD, Baillie R, Han X, Trojanowski JQ, Shaw LM, Martins R, Weiner MW, Trushina E, Toledo JB, Meikle PJ, Bennett DA, Krumsiek J, Doraiswamy PM, Saykin AJ, Kaddurah-Daouk R, Kastenmüller G. Arnold M, et al. Among authors: meikle pj. Nat Commun. 2020 Mar 2;11(1):1148. doi: 10.1038/s41467-020-14959-w. Nat Commun. 2020. PMID: 32123170 Free PMC article.
Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease.
Lim WLF, Huynh K, Chatterjee P, Martins I, Jayawardana KS, Giles C, Mellett NA, Laws SM, Bush AI, Rowe CC, Villemagne VL, Ames D, Drew BG, Masters CL, Meikle PJ, Martins RN; AIBL research group. Lim WLF, et al. Among authors: meikle pj. J Alzheimers Dis. 2020;76(1):303-315. doi: 10.3233/JAD-191304. J Alzheimers Dis. 2020. PMID: 32474467 Free PMC article.
321 results