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A lipid atlas of human and mouse immune cells provides insights into ferroptosis susceptibility.
Morgan PK, Pernes G, Huynh K, Giles C, Paul S, Smith AAT, Mellett NA, Liang A, van Buuren-Milne T, Veiga CB, Collins TJC, Xu Y, Lee MKS, De Silva TM, Meikle PJ, Lancaster GI, Murphy AJ. Morgan PK, et al. Among authors: meikle pj. Nat Cell Biol. 2024 Apr;26(4):645-659. doi: 10.1038/s41556-024-01377-z. Epub 2024 Apr 8. Nat Cell Biol. 2024. PMID: 38589531
Imputation of plasma lipid species to facilitate integration of lipidomic datasets.
Dakic A, Wu J, Wang T, Huynh K, Mellett N, Duong T, Beyene HB, Magliano DJ, Shaw JE, Carrington MJ, Inouye M, Yang JY, Figtree GA, Curran JE, Blangero J, Simes J; LIPID Study Investigators; Giles C, Meikle PJ. Dakic A, et al. Among authors: meikle pj. Nat Commun. 2024 Feb 20;15(1):1540. doi: 10.1038/s41467-024-45838-3. Nat Commun. 2024. PMID: 38378775 Free PMC article.
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice.
Yew MJ, Heywood SE, Ng J, West OM, Pal M, Kueh A, Lancaster GI, Myers S, Yang C, Liu Y, Reibe S, Mellett NA, Meikle PJ, Febbraio MA, Greening DW, Drew BG, Henstridge DC. Yew MJ, et al. Among authors: meikle pj. Diabetes Obes Metab. 2024 May;26(5):1731-1745. doi: 10.1111/dom.15484. Epub 2024 Feb 13. Diabetes Obes Metab. 2024. PMID: 38351663
Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer's disease.
Marshall JPS, Huynh K, Lancaster GI, Ng J, Collins JM, Pernes G, Liang A, Featherby T, Mellet NA, Drew BG, Calkin AC, King AE, Meikle PJ, Febbraio MA, Adlard PA, Henstridge DC. Marshall JPS, et al. Among authors: meikle pj. iScience. 2024 Jan 4;27(2):108800. doi: 10.1016/j.isci.2024.108800. eCollection 2024 Feb 16. iScience. 2024. PMID: 38292430 Free PMC article.
A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic analysis.
Schweickart A, Batra R, Neth BJ, Martino C, Shenhav L, Zhang AR, Shi P, Karu N, Huynh K, Meikle PJ, Schimmel L, Dilmore AH, Blennow K, Zetterberg H, Blach C, Dorrestein PC, Knight R; Alzheimer’s Gut Microbiome Project Consortium; Craft S, Kaddurah-Daouk R, Krumsiek J. Schweickart A, et al. Among authors: meikle pj. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298990. doi: 10.1101/2023.11.27.23298990. medRxiv. 2023. PMID: 38076824 Free PMC article. Preprint.
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity.
Martin SD, Connor T, Sanigorski A, McEwen KA, Henstridge DC, Nijagal B, De Souza D, Tull DL, Meikle PJ, Kowalski GM, Bruce CR, Gregorevic P, Febbraio MA, Collier FM, Walder KR, McGee SL. Martin SD, et al. Among authors: meikle pj. Cell Death Dis. 2023 Dec 1;14(12):787. doi: 10.1038/s41419-023-06319-5. Cell Death Dis. 2023. PMID: 38040704 Free PMC article.
Next Generation, Modifiable Cardiometabolic Biomarkers: Mitochondrial Adaptation and Metabolic Resilience: A Scientific Statement From the American Heart Association.
Mietus-Snyder M, Perak AM, Cheng S, Hayman LL, Haynes N, Meikle PJ, Shah SH, Suglia SF; American Heart Association Atherosclerosis, Hypertension and Obesity in the Young Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Lifestyle and Cardiometabolic Health; Council on Arteriosclerosis, Thrombosis and Vascular Biology; and Council on Cardiovascular and Stroke Nursing. Mietus-Snyder M, et al. Among authors: meikle pj. Circulation. 2023 Nov 28;148(22):1827-1845. doi: 10.1161/CIR.0000000000001185. Epub 2023 Oct 30. Circulation. 2023. PMID: 37902008 Free article. Review.
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
Jo T, Kim J, Bice P, Huynh K, Wang T, Arnold M, Meikle PJ, Giles C, Kaddurah-Daouk R, Saykin AJ, Nho K; Alzheimer's Disease Metabolomics Consortium (ADMC); Alzheimer's Disease Neuroimaging Initiative (ADNI). Jo T, et al. Among authors: meikle pj. EBioMedicine. 2023 Nov;97:104820. doi: 10.1016/j.ebiom.2023.104820. Epub 2023 Oct 7. EBioMedicine. 2023. PMID: 37806288 Free PMC article.
307 results