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Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.
Loaëc N, Attanasio E, Villiers B, Durieu E, Tahtouh T, Cam M, Davis RA, Alencar A, Roué M, Bourguet-Kondracki ML, Proksch P, Limanton E, Guiheneuf S, Carreaux F, Bazureau JP, Klautau M, Meijer L. Loaëc N, et al. Among authors: meijer l. Mar Drugs. 2017 Oct 17;15(10):316. doi: 10.3390/md15100316. Mar Drugs. 2017. PMID: 29039762 Free PMC article. Review.
Anticancer alkaloid lamellarins inhibit protein kinases.
Baunbaek D, Trinkler N, Ferandin Y, Lozach O, Ploypradith P, Rucirawat S, Ishibashi F, Iwao M, Meijer L. Baunbaek D, et al. Among authors: meijer l. Mar Drugs. 2008;6(4):514-27. doi: 10.3390/md20080026. Epub 2008 Oct 7. Mar Drugs. 2008. PMID: 19172192 Free PMC article.
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Debdab M, Carreaux F, Renault S, Soundararajan M, Fedorov O, Filippakopoulos P, Lozach O, Babault L, Tahtouh T, Baratte B, Ogawa Y, Hagiwara M, Eisenreich A, Rauch U, Knapp S, Meijer L, Bazureau JP. Debdab M, et al. Among authors: meijer l. J Med Chem. 2011 Jun 23;54(12):4172-86. doi: 10.1021/jm200274d. Epub 2011 May 26. J Med Chem. 2011. PMID: 21615147
An efficient approach to dispacamide A and its derivatives.
Guihéneuf S, Paquin L, Carreaux F, Durieu E, Meijer L, Bazureau JP. Guihéneuf S, et al. Among authors: meijer l. Org Biomol Chem. 2012 Feb 7;10(5):978-87. doi: 10.1039/c1ob06161e. Epub 2011 Dec 8. Org Biomol Chem. 2012. PMID: 22159215
474 results