Meijer L - Search Results

1

Synthesis and kinase inhibitory activity of novel substituted indigoids.

Beauchard A, Laborie H, Rouillard H, Lozach O, Ferandin Y, Le Guével R, Guguen-Guillouzo C, Meijer L, Besson T, Thiéry V. Beauchard A, et al. Among authors: meijer l. Bioorg Med Chem. 2009 Sep 1;17(17):6257-63. doi: 10.1016/j.bmc.2009.07.051. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19665384

2

Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration.

Loyer P, Glaise D, Cariou S, Baffet G, Meijer L, Guguen-Guillouzo C. Loyer P, et al. Among authors: meijer l. J Biol Chem. 1994 Jan 28;269(4):2491-500. J Biol Chem. 1994. PMID: 8300575 Free article.

3

Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases.

Legraverend M, Ludwig O, Bisagni E, Leclerc S, Meijer L. Legraverend M, et al. Among authors: meijer l. Bioorg Med Chem Lett. 1998 Apr 7;8(7):793-8. doi: 10.1016/s0960-894x(98)00097-3. Bioorg Med Chem Lett. 1998. PMID: 9871543

4

Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity.

Schultz C, Link A, Leost M, Zaharevitz DW, Gussio R, Sausville EA, Meijer L, Kunick C. Schultz C, et al. Among authors: meijer l. J Med Chem. 1999 Jul 29;42(15):2909-19. doi: 10.1021/jm9900570. J Med Chem. 1999. PMID: 10425100

5

Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors.

Legraverend M, Ludwig O, Bisagni E, Leclerc S, Meijer L, Giocanti N, Sadri R, Favaudon V. Legraverend M, et al. Among authors: meijer l. Bioorg Med Chem. 1999 Jul;7(7):1281-93. doi: 10.1016/s0968-0896(99)00064-4. Bioorg Med Chem. 1999. PMID: 10465404

6

2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity.

Kunick C, Schultz C, Lemcke T, Zaharevitz DW, Gussio R, Jalluri RK, Sausville EA, Leost M, Meijer L. Kunick C, et al. Among authors: meijer l. Bioorg Med Chem Lett. 2000 Mar 20;10(6):567-9. doi: 10.1016/s0960-894x(00)00048-2. Bioorg Med Chem Lett. 2000. PMID: 10741555

7

Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex.

Legraverend M, Tunnah P, Noble M, Ducrot P, Ludwig O, Grierson DS, Leost M, Meijer L, Endicott J. Legraverend M, et al. Among authors: meijer l. J Med Chem. 2000 Apr 6;43(7):1282-92. doi: 10.1021/jm9911130. J Med Chem. 2000. PMID: 10753466

8

Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1.

Jeong HW, Kim MR, Son KH, Han MY, Ha JH, Garnier M, Meijer L, Kwon BM. Jeong HW, et al. Among authors: meijer l. Bioorg Med Chem Lett. 2000 Aug 21;10(16):1819-22. doi: 10.1016/s0960-894x(00)00357-7. Bioorg Med Chem Lett. 2000. PMID: 10969976

9

Structure-based design and synthesis of 2-benzylidene-benzofuran-3-ones as flavopiridol mimics.

Schoepfer J, Fretz H, Chaudhuri B, Muller L, Seeber E, Meijer L, Lozach O, Vangrevelinghe E, Furet P. Schoepfer J, et al. Among authors: meijer l. J Med Chem. 2002 Apr 25;45(9):1741-7. doi: 10.1021/jm0108348. J Med Chem. 2002. PMID: 11960485

10

Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects.

Mettey Y, Gompel M, Thomas V, Garnier M, Leost M, Ceballos-Picot I, Noble M, Endicott J, Vierfond JM, Meijer L. Mettey Y, et al. Among authors: meijer l. J Med Chem. 2003 Jan 16;46(2):222-36. doi: 10.1021/jm020319p. J Med Chem. 2003. PMID: 12519061

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