Mehta S - Search Results

1

A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension.

Gunawardhana KL, Hong L, Rugira T, Uebbing S, Kucharczak J, Mehta S, Karunamuni DR, Cabera-Mendoza B, Gandotra N, Scharfe C, Polimanti R, Noonan JP, Mani A. Gunawardhana KL, et al. Among authors: mehta s. J Clin Invest. 2023 Feb 15;133(4):e160036. doi: 10.1172/JCI160036. J Clin Invest. 2023. PMID: 36602864 Free PMC article.

2

Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

Li G, Wang M, Caulk AW, Cilfone NA, Gujja S, Qin L, Chen PY, Chen Z, Yousef S, Jiao Y, He C, Jiang B, Korneva A, Bersi MR, Wang G, Liu X, Mehta S, Geirsson A, Gulcher JR, Chittenden TW, Simons M, Humphrey JD, Tellides G. Li G, et al. Among authors: mehta s. J Clin Invest. 2020 Mar 2;130(3):1233-1251. doi: 10.1172/JCI131048. J Clin Invest. 2020. PMID: 32039915 Free PMC article.

3

Prdm6 controls heart development by regulating neural crest cell differentiation and migration.

Hong L, Li N, Gasque V, Mehta S, Ye L, Wu Y, Li J, Gewies A, Ruland J, Hirschi KK, Eichmann A, Hendry C, van Dijk D, Mani A. Hong L, et al. Among authors: mehta s. JCI Insight. 2022 Feb 2;7(4):e156046. doi: 10.1172/jci.insight.156046. JCI Insight. 2022. PMID: 35108221 Free PMC article.

4

Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response.

Sahraei M, Chaube B, Liu Y, Sun J, Kaplan A, Price NL, Ding W, Oyaghire S, García-Milian R, Mehta S, Reshetnyak YK, Bahal R, Fiorina P, Glazer PM, Rimm DL, Fernández-Hernando C, Suárez Y. Sahraei M, et al. Among authors: mehta s. J Clin Invest. 2019 Dec 2;129(12):5518-5536. doi: 10.1172/JCI127125. J Clin Invest. 2019. PMID: 31710308 Free PMC article.

5

MicroRNA-1 protects the endothelium in acute lung injury.

Korde A, Haslip M, Pednekar P, Khan A, Chioccioli M, Mehta S, Lopez-Giraldez F, Bermejo S, Rojas M, Dela Cruz C, Matthay MA, Pober JS, Pierce RW, Takyar SS. Korde A, et al. Among authors: mehta s. JCI Insight. 2023 Sep 22;8(18):e164816. doi: 10.1172/jci.insight.164816. JCI Insight. 2023. PMID: 37737266 Free PMC article.

6

Excessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice.

Spronck B, Latorre M, Wang M, Mehta S, Caulk AW, Ren P, Ramachandra AB, Murtada SI, Rojas A, He CS, Jiang B, Bersi MR, Tellides G, Humphrey JD. Spronck B, et al. Among authors: mehta s. J R Soc Interface. 2021 Jul;18(180):20210336. doi: 10.1098/rsif.2021.0336. Epub 2021 Jul 28. J R Soc Interface. 2021. PMID: 34314650 Free PMC article.

7

Early cellular and molecular signatures correlate with severity of West Nile virus infection.

Lee HJ, Zhao Y, Fleming I, Mehta S, Wang X, Wyk BV, Ronca SE, Kang H, Chou CH, Fatou B, Smolen KK, Levy O, Clish CB, Xavier RJ, Steen H, Hafler DA, Love JC, Shalek AK, Guan L, Murray KO, Kleinstein SH, Montgomery RR. Lee HJ, et al. Among authors: mehta s. iScience. 2023 Nov 2;26(12):108387. doi: 10.1016/j.isci.2023.108387. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047068 Free PMC article.

8

The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors.

Chiu JE, Thekkiniath J, Mehta S, Müller C, Bracher F, Ben Mamoun C. Chiu JE, et al. Among authors: mehta s. J Biol Chem. 2019 Oct 4;294(40):14757-14767. doi: 10.1074/jbc.RA119.009791. Epub 2019 Aug 13. J Biol Chem. 2019. PMID: 31409644 Free PMC article.

9

Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas.

Zhang H, Li B, Huang Q, López-Giráldez F, Tanaka Y, Lin Q, Mehta S, Wang G, Graham M, Liu X, Park IH, Eichmann A, Min W, Zhou JH. Zhang H, et al. Among authors: mehta s. Nat Commun. 2022 Dec 10;13(1):7637. doi: 10.1038/s41467-022-35262-w. Nat Commun. 2022. PMID: 36496409 Free PMC article.

10

Single-cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV.

Farhadian SF, Mehta SS, Zografou C, Robertson K, Price RW, Pappalardo J, Chiarella J, Hafler DA, Spudich SS. Farhadian SF, et al. Among authors: mehta ss. JCI Insight. 2018 Sep 20;3(18):e121718. doi: 10.1172/jci.insight.121718. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232286 Free PMC article.

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