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Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors.
Stevens CM, Babii SO, Pandya AN, Li W, Li Y, Mehla J, Scott R, Hegde P, Prathipati PK, Acharya A, Liu J, Gumbart JC, North J, Jackson M, Zgurskaya HI. Stevens CM, et al. Among authors: mehla j. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2113963119. doi: 10.1073/pnas.2113963119. Epub 2022 Jul 19. Proc Natl Acad Sci U S A. 2022. PMID: 35858440 Free PMC article.
Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa.
Mehla J, Malloci G, Mansbach R, López CA, Tsivkovski R, Haynes K, Leus IV, Grindstaff SB, Cascella RH, D'Cunha N, Herndon L, Hengartner NW, Margiotta E, Atzori A, Vargiu AV, Manrique PD, Walker JK, Lomovskaya O, Ruggerone P, Gnanakaran S, Rybenkov VV, Zgurskaya HI. Mehla J, et al. mBio. 2021 Jan 19;12(1):e02785-20. doi: 10.1128/mBio.02785-20. mBio. 2021. PMID: 33468691 Free PMC article.
The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance.
Downes MT, Mehla J, Ananthaswamy N, Wakschlag A, Lamonde M, Dine E, Ambudkar SV, Golin J. Downes MT, et al. Among authors: mehla j. Antimicrob Agents Chemother. 2013 Feb;57(2):1025-34. doi: 10.1128/AAC.02133-12. Epub 2012 Dec 17. Antimicrob Agents Chemother. 2013. PMID: 23254431 Free PMC article.
ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis.
Mehla J, Liechti G, Morgenstein RM, Caufield JH, Hosseinnia A, Gagarinova A, Phanse S, Goodacre N, Brockett M, Sakhawalkar N, Babu M, Xiao R, Montelione GT, Vorobiev S, den Blaauwen T, Hunt JF, Uetz P. Mehla J, et al. J Biol Chem. 2021 Jan-Jun;296:100700. doi: 10.1016/j.jbc.2021.100700. Epub 2021 Apr 23. J Biol Chem. 2021. PMID: 33895137 Free PMC article.
56 results