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PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.
Wu Q, Nie DY, Ba-Alawi W, Ji Y, Zhang Z, Cruickshank J, Haight J, Ciamponi FE, Chen J, Duan S, Shen Y, Liu J, Marhon SA, Mehdipour P, Szewczyk MM, Dogan-Artun N, Chen W, Zhang LX, Deblois G, Prinos P, Massirer KB, Barsyte-Lovejoy D, Jin J, De Carvalho DD, Haibe-Kains B, Wang X, Cescon DW, Lupien M, Arrowsmith CH. Wu Q, et al. Among authors: mehdipour p. Nat Chem Biol. 2022 Aug;18(8):821-830. doi: 10.1038/s41589-022-01024-4. Epub 2022 May 16. Nat Chem Biol. 2022. PMID: 35578032 Free PMC article.
The role of DNA-demethylating agents in cancer therapy.
Mehdipour P, Murphy T, De Carvalho DD. Mehdipour P, et al. Pharmacol Ther. 2020 Jan;205:107416. doi: 10.1016/j.pharmthera.2019.107416. Epub 2019 Oct 15. Pharmacol Ther. 2020. PMID: 31626871 Review.
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells.
Loo Yau H, Bell E, Ettayebi I, de Almeida FC, Boukhaled GM, Shen SY, Allard D, Morancho B, Marhon SA, Ishak CA, Gonzaga IM, da Silva Medina T, Singhania R, Chakravarthy A, Chen R, Mehdipour P, Pommey S, Klein C, Amarante-Mendes GP, Roulois D, Arribas J, Stagg J, Brooks DG, De Carvalho DD. Loo Yau H, et al. Among authors: mehdipour p. Mol Cell. 2021 Apr 1;81(7):1469-1483.e8. doi: 10.1016/j.molcel.2021.01.038. Epub 2021 Feb 19. Mol Cell. 2021. PMID: 33609448 Free article.
The next generation of DNMT inhibitors.
Mehdipour P, Chen R, De Carvalho DD. Mehdipour P, et al. Nat Cancer. 2021 Oct;2(10):1000-1001. doi: 10.1038/s43018-021-00271-z. Nat Cancer. 2021. PMID: 35121882 No abstract available.
macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.
Nikolic A, Maule F, Bobyn A, Ellestad K, Paik S, Marhon SA, Mehdipour P, Lun X, Chen HM, Mallard C, Hay AJ, Johnston MJ, Gafuik CJ, Zemp FJ, Shen Y, Ninkovic N, Osz K, Labit E, Berger ND, Brownsey DK, Kelly JJ, Biernaskie J, Dirks PB, Derksen DJ, Jones SJM, Senger DL, Chan JA, Mahoney DJ, De Carvalho DD, Gallo M. Nikolic A, et al. Among authors: mehdipour p. Nat Commun. 2023 May 27;14(1):3062. doi: 10.1038/s41467-023-38919-2. Nat Commun. 2023. PMID: 37244935 Free PMC article.
Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia.
de Castro FA, Mehdipour P, Chakravarthy A, Ettayebi I, Loo Yau H, Medina TS, Marhon SA, de Almeida FC, Bianco TM, Arruda AGF, Devlin R, de Figueiredo-Pontes LL, Chahud F, da Costa Cacemiro M, Minden MD, Gupta V, De Carvalho DD. de Castro FA, et al. Among authors: mehdipour p. Br J Haematol. 2024 Jan;204(1):206-220. doi: 10.1111/bjh.19107. Epub 2023 Sep 19. Br J Haematol. 2024. PMID: 37726227
Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer.
Hosseini A, Lindholm HT, Chen R, Mehdipour P, Marhon SA, Ishak CA, Moore PC, Classon M, Di Gioacchino A, Greenbaum B, De Carvalho DD. Hosseini A, et al. Among authors: mehdipour p. Cell Rep. 2024 Feb 27;43(2):113684. doi: 10.1016/j.celrep.2024.113684. Epub 2024 Jan 22. Cell Rep. 2024. PMID: 38261511 Free article.
Epigenetic alterations in acute myeloid leukemias.
Mehdipour P, Santoro F, Minucci S. Mehdipour P, et al. FEBS J. 2015 May;282(9):1786-800. doi: 10.1111/febs.13142. Epub 2014 Nov 24. FEBS J. 2015. PMID: 25369368 Free article. Review.
108 results