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A live dengue virus vaccine carrying a chimeric envelope glycoprotein elicits dual DENV2-DENV4 serotype-specific immunity.
Young E, Yount B, Pantoja P, Henein S, Meganck RM, McBride J, Munt JE, Baric TJ, Zhu D, Scobey T, Dong S, Tse LV, Martinez MI, Burgos AG, Graham RL, White L, DeSilva A, Sariol CA, Baric RS. Young E, et al. Among authors: meganck rm. Nat Commun. 2023 Mar 13;14(1):1371. doi: 10.1038/s41467-023-36702-x. Nat Commun. 2023. PMID: 36914616 Free PMC article.
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.
Schäfer A, Martinez DR, Won JJ, Meganck RM, Moreira FR, Brown AJ, Gully KL, Zweigart MR, Conrad WS, May SR, Dong S, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, Bannister R, Feng JY, Bilello JP, Cihlar T, Mackman RL, Montgomery SA, Baric RS, Sheahan TP. Schäfer A, et al. Among authors: meganck rm. Sci Transl Med. 2022 May 4;14(643):eabm3410. doi: 10.1126/scitranslmed.abm3410. Epub 2022 May 4. Sci Transl Med. 2022. PMID: 35315683 Free PMC article.
Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection.
Tse LV, Meganck RM, Araba KC, Yount BL, Shaffer KM, Hou YJ, Munt JE, Adams LE, Wykoff JA, Morowitz JM, Dong S, Magness ST, Marzluff WF, Gonzalez LM, Ehre C, Baric RS. Tse LV, et al. Among authors: meganck rm. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2118126119. doi: 10.1073/pnas.2118126119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476513 Free PMC article.
Durability of Heterologous and Homologous COVID-19 Vaccine Boosts.
Tan CS, Collier AY, Yu J, Liu J, Chandrashekar A, McMahan K, Jacob-Dolan C, He X, Roy V, Hauser BM, Munt JE, Mallory ML, Mattocks M, Powers JM, Meganck RM, Rowe M, Hemond R, Bondzie EA, Jaegle KH, Baric RS, Schmidt AG, Alter G, Le Gars M, Sadoff J, Barouch DH. Tan CS, et al. Among authors: meganck rm. JAMA Netw Open. 2022 Aug 1;5(8):e2226335. doi: 10.1001/jamanetworkopen.2022.26335. JAMA Netw Open. 2022. PMID: 35947380 Free PMC article.
27 results