Medvedev S - Search Results

1

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models.

Kim H, Xu H, George E, Hallberg D, Kumar S, Jagannathan V, Medvedev S, Kinose Y, Devins K, Verma P, Ly K, Wang Y, Greenberg RA, Schwartz L, Johnson N, Scharpf RB, Mills GB, Zhang R, Velculescu VE, Brown EJ, Simpkins F. Kim H, et al. Among authors: medvedev s. Nat Commun. 2020 Jul 24;11(1):3726. doi: 10.1038/s41467-020-17127-2. Nat Commun. 2020. PMID: 32709856 Free PMC article.

2

CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models.

Xu H, George E, Kinose Y, Kim H, Shah JB, Peake JD, Ferman B, Medvedev S, Murtha T, Barger CJ, Devins KM, D'Andrea K, Wubbenhorst B, Schwartz LE, Hwang WT, Mills GB, Nathanson KL, Karpf AR, Drapkin R, Brown EJ, Simpkins F. Xu H, et al. Among authors: medvedev s. Cell Rep Med. 2021 Sep 23;2(9):100394. doi: 10.1016/j.xcrm.2021.100394. eCollection 2021 Sep 21. Cell Rep Med. 2021. PMID: 34622231 Free PMC article.

3

Humanized Patient-Derived Xenograft Models of Ovarian Cancer.

Gitto SB, George E, Medvedev S, Simpkins F, Powell DJ Jr. Gitto SB, et al. Among authors: medvedev s. Methods Mol Biol. 2022;2424:255-274. doi: 10.1007/978-1-0716-1956-8_17. Methods Mol Biol. 2022. PMID: 34918300

4

An autologous humanized patient-derived-xenograft platform to evaluate immunotherapy in ovarian cancer.

Gitto SB, Kim H, Rafail S, Omran DK, Medvedev S, Kinose Y, Rodriguez-Garcia A, Flowers AJ, Xu H, Schwartz LE, Powell DJ Jr, Simpkins F. Gitto SB, et al. Among authors: medvedev s. Gynecol Oncol. 2020 Jan;156(1):222-232. doi: 10.1016/j.ygyno.2019.10.011. Epub 2019 Dec 7. Gynecol Oncol. 2020. PMID: 31818495

5

Specificity of calcium/calmodulin-dependent protein kinases in mouse egg activation.

Medvedev S, Stein P, Schultz RM. Medvedev S, et al. Cell Cycle. 2014;13(9):1482-8. doi: 10.4161/cc.28432. Epub 2014 Mar 11. Cell Cycle. 2014. PMID: 24626179 Free PMC article.

6

Transgenic RNAi-mediated reduction of MSY2 in mouse oocytes results in reduced fertility.

Yu J, Deng M, Medvedev S, Yang J, Hecht NB, Schultz RM. Yu J, et al. Among authors: medvedev s. Dev Biol. 2004 Apr 1;268(1):195-206. doi: 10.1016/j.ydbio.2003.12.020. Dev Biol. 2004. PMID: 15031116 Free article.

7

The DNA/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells.

Yang J, Medvedev S, Reddi PP, Schultz RM, Hecht NB. Yang J, et al. Among authors: medvedev s. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1513-8. doi: 10.1073/pnas.0404685102. Epub 2005 Jan 21. Proc Natl Acad Sci U S A. 2005. PMID: 15665108 Free PMC article.

8

Deletion of the DNA/RNA-binding protein MSY2 leads to post-meiotic arrest.

Yang J, Medvedev S, Yu J, Schultz RM, Hecht NB. Yang J, et al. Among authors: medvedev s. Mol Cell Endocrinol. 2006 May 16;250(1-2):20-4. doi: 10.1016/j.mce.2005.12.019. Epub 2006 Jan 18. Mol Cell Endocrinol. 2006. PMID: 16413673 Review.

9

In the absence of the mouse DNA/RNA-binding protein MSY2, messenger RNA instability leads to spermatogenic arrest.

Yang J, Morales CR, Medvedev S, Schultz RM, Hecht NB. Yang J, et al. Among authors: medvedev s. Biol Reprod. 2007 Jan;76(1):48-54. doi: 10.1095/biolreprod.106.055095. Epub 2006 Oct 11. Biol Reprod. 2007. PMID: 17035640

10

Absence of MSY2 in mouse oocytes perturbs oocyte growth and maturation, RNA stability, and the transcriptome.

Medvedev S, Pan H, Schultz RM. Medvedev S, et al. Biol Reprod. 2011 Sep;85(3):575-83. doi: 10.1095/biolreprod.111.091710. Epub 2011 May 25. Biol Reprod. 2011. PMID: 21613634 Free PMC article.

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