The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Preininger AM, Van Eps N, Yu NJ, Medkova M, Hubbell WL, Hamm HE.
Preininger AM, et al. Among authors: medkova m.
Biochemistry. 2003 Jul 8;42(26):7931-41. doi: 10.1021/bi0345438.
Biochemistry. 2003.
PMID: 12834345
This is in contrast to the high mobility of this region in nonmyristoylated Galpha(i) [Medkova, M., et al. (2002) Biochemistry 41, 9962-9972]. Steady state fluorescence measurements revealed pronounced increases in fluorescence upon activation for residues 14-17 and …
This is in contrast to the high mobility of this region in nonmyristoylated Galpha(i) [Medkova, M., et al. (2002) Biochemistry …