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Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating alpha-asarone-based HMG-CoA reductase inhibitors.
Argüelles N, Sánchez-Sandoval E, Mendieta A, Villa-Tanaca L, Garduño-Siciliano L, Jiménez F, Cruz Mdel C, Medina-Franco JL, Chamorro-Cevallos G, Tamariz J. Argüelles N, et al. Bioorg Med Chem. 2010 Jun 15;18(12):4238-48. doi: 10.1016/j.bmc.2010.04.096. Epub 2010 May 10. Bioorg Med Chem. 2010. PMID: 20576575
Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent.
Navarrete-Vázquez G, Alaniz-Palacios A, Hidalgo-Figueroa S, González-Acevedo C, Ávila-Villarreal G, Estrada-Soto S, Webster SP, Medina-Franco JL, López-Vallejo F, Guerrero-Álvarez J, Tlahuext H. Navarrete-Vázquez G, et al. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3244-7. doi: 10.1016/j.bmcl.2013.03.122. Epub 2013 Apr 5. Bioorg Med Chem Lett. 2013. PMID: 23597793
Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors.
Mendieta A, Jiménez F, Garduño-Siciliano L, Mojica-Villegas A, Rosales-Acosta B, Villa-Tanaca L, Chamorro-Cevallos G, Medina-Franco JL, Meurice N, Gutiérrez RU, Montiel LE, Cruz Mdel C, Tamariz J. Mendieta A, et al. Bioorg Med Chem. 2014 Nov 1;22(21):5871-82. doi: 10.1016/j.bmc.2014.09.022. Epub 2014 Sep 19. Bioorg Med Chem. 2014. PMID: 25311563
242 results