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A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.
Vecchione L, Gambino V, Raaijmakers J, Schlicker A, Fumagalli A, Russo M, Villanueva A, Beerling E, Bartolini A, Mollevi DG, El-Murr N, Chiron M, Calvet L, Nicolazzi C, Combeau C, Henry C, Simon IM, Tian S, in 't Veld S, D'ario G, Mainardi S, Beijersbergen RL, Lieftink C, Linn S, Rumpf-Kienzl C, Delorenzi M, Wessels L, Salazar R, Di Nicolantonio F, Bardelli A, van Rheenen J, Medema RH, Tejpar S, Bernards R. Vecchione L, et al. Among authors: medema rh. Cell. 2016 Apr 7;165(2):317-30. doi: 10.1016/j.cell.2016.02.059. Cell. 2016. PMID: 27058664 Free article.
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.
van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, van der Horn K, Batlle E, Coudreuse D, Haramis AP, Tjon-Pon-Fong M, Moerer P, van den Born M, Soete G, Pals S, Eilers M, Medema R, Clevers H. van de Wetering M, et al. Cell. 2002 Oct 18;111(2):241-50. doi: 10.1016/s0092-8674(02)01014-0. Cell. 2002. PMID: 12408868 Free article.
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids.
Roodhart JM, Daenen LG, Stigter EC, Prins HJ, Gerrits J, Houthuijzen JM, Gerritsen MG, Schipper HS, Backer MJ, van Amersfoort M, Vermaat JS, Moerer P, Ishihara K, Kalkhoven E, Beijnen JH, Derksen PW, Medema RH, Martens AC, Brenkman AB, Voest EE. Roodhart JM, et al. Among authors: medema rh. Cancer Cell. 2011 Sep 13;20(3):370-83. doi: 10.1016/j.ccr.2011.08.010. Cancer Cell. 2011. PMID: 21907927 Free article.
Switching Polo-like kinase-1 on and off in time and space.
Bruinsma W, Raaijmakers JA, Medema RH. Bruinsma W, et al. Among authors: medema rh. Trends Biochem Sci. 2012 Dec;37(12):534-42. doi: 10.1016/j.tibs.2012.09.005. Epub 2012 Nov 6. Trends Biochem Sci. 2012. PMID: 23141205 Review.
Systematic dissection of dynein regulators in mitosis.
Raaijmakers JA, Tanenbaum ME, Medema RH. Raaijmakers JA, et al. Among authors: medema rh. J Cell Biol. 2013 Apr 15;201(2):201-15. doi: 10.1083/jcb.201208098. J Cell Biol. 2013. PMID: 23589491 Free PMC article.
248 results