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Patched-2 functions to limit Patched-1 deficient skin cancer growth.
Veenstra VL, Dingjan I, Waasdorp C, Damhofer H, van der Wal AC, van Laarhoven HW, Medema JP, Bijlsma MF. Veenstra VL, et al. Among authors: medema jp. Cell Oncol (Dordr). 2018 Aug;41(4):427-437. doi: 10.1007/s13402-018-0381-9. Epub 2018 Jun 4. Cell Oncol (Dordr). 2018. PMID: 29869097 Free PMC article.
Stromal SPOCK1 supports invasive pancreatic cancer growth.
Veenstra VL, Damhofer H, Waasdorp C, Steins A, Kocher HM, Medema JP, van Laarhoven HW, Bijlsma MF. Veenstra VL, et al. Among authors: medema jp. Mol Oncol. 2017 Aug;11(8):1050-1064. doi: 10.1002/1878-0261.12073. Epub 2017 Jun 5. Mol Oncol. 2017. PMID: 28486750 Free PMC article.
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract.
Damhofer H, Ebbing EA, Steins A, Welling L, Tol JA, Krishnadath KK, van Leusden T, van de Vijver MJ, Besselink MG, Busch OR, van Berge Henegouwen MI, van Delden O, Meijer SL, Dijk F, Medema JP, van Laarhoven HW, Bijlsma MF. Damhofer H, et al. Among authors: medema jp. J Transl Med. 2015 Apr 11;13:115. doi: 10.1186/s12967-015-0469-1. J Transl Med. 2015. PMID: 25884700 Free PMC article.
High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1.
Steins A, van Mackelenbergh MG, van der Zalm AP, Klaassen R, Serrels B, Goris SG, Kocher HM, Waasdorp C, de Jong JH, Tekin C, Besselink MG, Busch OR, van de Vijver MJ, Verheij J, Dijk F, van Tienhoven G, Wilmink JW, Medema JP, van Laarhoven HW, Bijlsma MF. Steins A, et al. Among authors: medema jp. EMBO Rep. 2020 May 6;21(5):e48780. doi: 10.15252/embr.201948780. Epub 2020 Mar 16. EMBO Rep. 2020. PMID: 32173982 Free PMC article.
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma.
Ebbing EA, van der Zalm AP, Steins A, Creemers A, Hermsen S, Rentenaar R, Klein M, Waasdorp C, Hooijer GKJ, Meijer SL, Krishnadath KK, Punt CJA, van Berge Henegouwen MI, Gisbertz SS, van Delden OM, Hulshof MCCM, Medema JP, van Laarhoven HWM, Bijlsma MF. Ebbing EA, et al. Among authors: medema jp. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2237-2242. doi: 10.1073/pnas.1820459116. Epub 2019 Jan 22. Proc Natl Acad Sci U S A. 2019. PMID: 30670657 Free PMC article.
Chemoradiation induces epithelial-to-mesenchymal transition in esophageal adenocarcinoma.
Steins A, Ebbing EA, Creemers A, van der Zalm AP, Jibodh RA, Waasdorp C, Meijer SL, van Delden OM, Krishnadath KK, Hulshof MCCM, Bennink RJ, Punt CJA, Medema JP, Bijlsma MF, van Laarhoven HWM. Steins A, et al. Among authors: medema jp. Int J Cancer. 2019 Nov 15;145(10):2792-2803. doi: 10.1002/ijc.32364. Epub 2019 May 7. Int J Cancer. 2019. PMID: 31018252 Free PMC article.
Rapid stromal remodeling by short-term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma.
Steins A, Klaassen R, Jacobs I, Schabel MC, van Lier MGJTB, Ebbing EA, Hectors SJ, Tas SW, Maracle CX, Punt CJA, Siebes M, Bergman JJGHM, Medema JP, Wilmink JW, Mathot RAA, Strijkers GJ, Bijlsma MF, van Laarhoven HWM. Steins A, et al. Among authors: medema jp. Mol Oncol. 2020 Apr;14(4):704-720. doi: 10.1002/1878-0261.12599. Epub 2020 Mar 3. Mol Oncol. 2020. PMID: 31733011 Free PMC article.
249 results