Mechoulam R - Search Results

1

Fenchone Derivatives as a Novel Class of CB2 Selective Ligands: Design, Synthesis, X-ray Structure and Therapeutic Potential.

Smoum R, Haj C, Hirsch S, Nemirovski A, Yekhtin Z, Bogoslavsky B, Bakshi GK, Chourasia M, Gallily R, Tam J, Mechoulam R. Smoum R, et al. Among authors: mechoulam r. Molecules. 2022 Feb 18;27(4):1382. doi: 10.3390/molecules27041382. Molecules. 2022. PMID: 35209170 Free PMC article.

2

CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency.

Smoum R, Baraghithy S, Chourasia M, Breuer A, Mussai N, Attar-Namdar M, Kogan NM, Raphael B, Bolognini D, Cascio MG, Marini P, Pertwee RG, Shurki A, Mechoulam R, Bab I. Smoum R, et al. Among authors: mechoulam r. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8774-9. doi: 10.1073/pnas.1503395112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124120 Free PMC article.

3

HU-671, a Novel Oleoyl Serine Derivative, Exhibits Enhanced Efficacy in Reversing Ovariectomy-Induced Osteoporosis and Bone Marrow Adiposity.

Baraghithy S, Smoum R, Attar-Namdar M, Mechoulam R, Bab I, Tam J. Baraghithy S, et al. Among authors: mechoulam r. Molecules. 2019 Oct 16;24(20):3719. doi: 10.3390/molecules24203719. Molecules. 2019. PMID: 31623098 Free PMC article.

4

Novel CBG Derivatives Can Reduce Inflammation, Pain and Obesity.

Kogan NM, Lavi Y, Topping LM, Williams RO, McCann FE, Yekhtin Z, Feldmann M, Gallily R, Mechoulam R. Kogan NM, et al. Among authors: mechoulam r. Molecules. 2021 Sep 15;26(18):5601. doi: 10.3390/molecules26185601. Molecules. 2021. PMID: 34577072 Free PMC article.

5

Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury.

Mann A, Smoum R, Trembovler V, Alexandrovich A, Breuer A, Mechoulam R, Shohami E. Mann A, et al. Among authors: mechoulam r. J Neuroimmune Pharmacol. 2015 Jun;10(2):356-63. doi: 10.1007/s11481-015-9595-z. Epub 2015 Feb 27. J Neuroimmune Pharmacol. 2015. PMID: 25721934

6

HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells.

Kozela E, Haj C, Hanuš L, Chourasia M, Shurki A, Juknat A, Kaushansky N, Mechoulam R, Vogel Z. Kozela E, et al. Among authors: mechoulam r. Chem Biol Drug Des. 2016 Jan;87(1):143-53. doi: 10.1111/cbdd.12637. Epub 2015 Sep 16. Chem Biol Drug Des. 2016. PMID: 26259697

7

Potential combinations of endocannabinoid/endocannabinoid-like compounds and antibiotics against methicillin-resistant Staphylococcus aureus.

Feldman M, Smoum R, Mechoulam R, Steinberg D. Feldman M, et al. Among authors: mechoulam r. PLoS One. 2020 Apr 15;15(4):e0231583. doi: 10.1371/journal.pone.0231583. eCollection 2020. PLoS One. 2020. PMID: 32294120 Free PMC article.

8

HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid.

Haj CG, Sumariwalla PF, Hanuš L, Kogan NM, Yektin Z, Mechoulam R, Feldmann M, Gallily R. Haj CG, et al. Among authors: mechoulam r. J Pharmacol Exp Ther. 2015 Oct;355(1):66-75. doi: 10.1124/jpet.115.226100. Epub 2015 Aug 13. J Pharmacol Exp Ther. 2015. PMID: 26272937 Free PMC article.

9

Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT_1A receptor-mediated suppression of nausea and anxiety in rats.

Pertwee RG, Rock EM, Guenther K, Limebeer CL, Stevenson LA, Haj C, Smoum R, Parker LA, Mechoulam R. Pertwee RG, et al. Among authors: mechoulam r. Br J Pharmacol. 2018 Jan;175(1):100-112. doi: 10.1111/bph.14073. Epub 2017 Dec 5. Br J Pharmacol. 2018. PMID: 29057454 Free PMC article.

10

N-Oleoyl Glycine and Its Derivatives Attenuate the Acquisition and Expression of Cocaine-Induced Behaviors.

Shahen-Zoabi S, Smoum R, Beiser T, Nemirovski A, Mechoulam R, Yaka R. Shahen-Zoabi S, et al. Among authors: mechoulam r. Cannabis Cannabinoid Res. 2023 Oct;8(5):812-823. doi: 10.1089/can.2022.0005. Epub 2022 May 31. Cannabis Cannabinoid Res. 2023. PMID: 35647907

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