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Tenascin-C is a driver of inflammation in the DSS model of colitis.
Ozanne J, Shek B, Stephen LA, Novak A, Milne E, Mclachlan G, Midwood KS, Farquharson C. Ozanne J, et al. Among authors: mclachlan g. Matrix Biol Plus. 2022 May 23;14:100112. doi: 10.1016/j.mbplus.2022.100112. eCollection 2022 Jun. Matrix Biol Plus. 2022. PMID: 35669358 Free PMC article.
Transfection efficiency and toxicity following delivery of naked plasmid DNA and cationic lipid-DNA complexes to ovine lung segments.
Emerson M, Renwick L, Tate S, Rhind S, Milne E, Painter HA, Boyd AC, McLachlan G, Griesenbach U, Cheng SH, Gill DR, Hyde SC, Baker A, Alton EW, Porteous DJ, Collie DD. Emerson M, et al. Among authors: mclachlan g. Mol Ther. 2003 Oct;8(4):646-53. doi: 10.1016/s1525-0016(03)00233-8. Mol Ther. 2003. PMID: 14529838 Free article.
Optimizing aerosol gene delivery and expression in the ovine lung.
McLachlan G, Baker A, Tennant P, Gordon C, Vrettou C, Renwick L, Blundell R, Cheng SH, Scheule RK, Davies L, Painter H, Coles RL, Lawton AE, Marriott C, Gill DR, Hyde SC, Griesenbach U, Alton EW, Boyd AC, Porteous DJ, Collie DD. McLachlan G, et al. Mol Ther. 2007 Feb;15(2):348-54. doi: 10.1038/sj.mt.6300058. Mol Ther. 2007. PMID: 17235313 Free article.
Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes.
Davies LA, McLachlan G, Sumner-Jones SG, Ferguson D, Baker A, Tennant P, Gordon C, Vrettou C, Baker E, Zhu J, Alton EW, Collie DD, Porteous DJ, Hyde SC, Gill DR. Davies LA, et al. Among authors: mclachlan g. Mol Ther. 2008 Jul;16(7):1283-90. doi: 10.1038/mt.2008.96. Epub 2008 May 20. Mol Ther. 2008. PMID: 18500249 Free article.
The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep.
Alton EW, Baker A, Baker E, Boyd AC, Cheng SH, Coles RL, Collie DD, Davidson H, Davies JC, Gill DR, Gordon C, Griesenbach U, Higgins T, Hyde SC, Innes JA, McCormick D, McGovern M, McLachlan G, Porteous DJ, Pringle I, Scheule RK, Shaw DJ, Smith S, Sumner-Jones SG, Tennant P, Vrettou C. Alton EW, et al. Among authors: mclachlan g. Biomaterials. 2013 Dec;34(38):10267-77. doi: 10.1016/j.biomaterials.2013.09.023. Epub 2013 Oct 3. Biomaterials. 2013. PMID: 24090839
192 results