McWilliams JC - Search Results

1

Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral beta-amino acid derivatives.

Ikemoto N, Tellers DM, Dreher SD, Liu J, Huang A, Rivera NR, Njolito E, Hsiao Y, McWilliams JC, Williams JM, Armstrong JD 3rd, Sun Y, Mathre DJ, Grabowski EJ, Tillyer RD. Ikemoto N, et al. Among authors: mcwilliams jc. J Am Chem Soc. 2004 Mar 17;126(10):3048-9. doi: 10.1021/ja038812t. J Am Chem Soc. 2004. PMID: 15012124

2

On the mechanism of an asymmetric alpha,beta-unsaturated carboxylic acid hydrogenation: application to the synthesis of a PGD2 receptor antagonist.

Tellers DM, McWilliams JC, Humphrey G, Journet M, DiMichele L, Hinksmon J, McKeown AE, Rosner T, Sun Y, Tillyer RD. Tellers DM, et al. Among authors: mcwilliams jc. J Am Chem Soc. 2006 Dec 27;128(51):17063-73. doi: 10.1021/ja0623358. J Am Chem Soc. 2006. PMID: 17177459

3

Enantioselective hydrogenation of N-H imines.

Hou G, Gosselin F, Li W, McWilliams JC, Sun Y, Weisel M, O'Shea PD, Chen CY, Davies IW, Zhang X. Hou G, et al. Among authors: mcwilliams jc. J Am Chem Soc. 2009 Jul 29;131(29):9882-3. doi: 10.1021/ja903319r. J Am Chem Soc. 2009. PMID: 19569686

4

An efficient catalyst for Pd-catalyzed carbonylation of aryl arenesulfonates.

Cai C, Rivera NR, Balsells J, Sidler RR, McWilliams JC, Shultz CS, Sun Y. Cai C, et al. Among authors: mcwilliams jc. Org Lett. 2006 Oct 26;8(22):5161-4. doi: 10.1021/ol062208g. Org Lett. 2006. PMID: 17048868

5

Catalytic enantioselective hydrogenation of N-alkoxycarbonyl hydrazones: a practical synthesis of chiral hydrazines.

Yoshikawa N, Tan L, McWilliams JC, Ramasamy D, Sheppard R. Yoshikawa N, et al. Among authors: mcwilliams jc. Org Lett. 2010 Jan 15;12(2):276-9. doi: 10.1021/ol902602c. Org Lett. 2010. PMID: 20017501

6

Highly enantioselective hydrogenation of aromatic-heteroaromatic ketones.

Chen CY, Reamer RA, Chilenski JR, McWilliams JC. Chen CY, et al. Among authors: mcwilliams jc. Org Lett. 2003 Dec 25;5(26):5039-42. doi: 10.1021/ol0360795. Org Lett. 2003. PMID: 14682759

7

Efficient synthesis of a trisubstituted 1,6-naphthyridone from acetonedicarboxylate and regioselective Suzuki arylation.

Chung JY, Cai C, McWilliams JC, Reamer RA, Dormer PG, Cvetovich RJ. Chung JY, et al. Among authors: mcwilliams jc. J Org Chem. 2005 Dec 9;70(25):10342-7. doi: 10.1021/jo0514927. J Org Chem. 2005. PMID: 16323843

8

Enantioselective nitrile anion cyclization to substituted pyrrolidines. A highly efficient synthesis of (3S,4R)-N-tert-butyl-4-arylpyrrolidine-3-carboxylic acid.

Chung JY, Cvetovich R, Amato J, McWilliams JC, Reamer R, DiMichele L. Chung JY, et al. Among authors: mcwilliams jc. J Org Chem. 2005 Apr 29;70(9):3592-601. doi: 10.1021/jo050178+. J Org Chem. 2005. PMID: 15844996

9

Stereoelectronic Effects in Ligand Design: Enantioselective Rhodium-Catalyzed Hydrogenation of Aliphatic Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib.

Li C, Wan F, Chen Y, Peng H, Tang W, Yu S, McWilliams JC, Mustakis J, Samp L, Maguire RJ. Li C, et al. Among authors: mcwilliams jc. Angew Chem Int Ed Engl. 2019 Sep 16;58(38):13573-13583. doi: 10.1002/anie.201908089. Epub 2019 Aug 13. Angew Chem Int Ed Engl. 2019. PMID: 31343811 Review.

10

Asymmetric synthesis of vabicaserin via oxidative multicomponent annulation and asymmetric hydrogenation of a 3,4-substituted quinolinium salt.

Dragan V, McWilliams JC, Miller R, Sutherland K, Dillon JL, O'Brien MK. Dragan V, et al. Among authors: mcwilliams jc. Org Lett. 2013 Jun 21;15(12):2942-5. doi: 10.1021/ol401029k. Epub 2013 Jun 10. Org Lett. 2013. PMID: 23751116

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