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Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL. Pickett EK, et al. Among authors: mcqueen j. Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044. Cell Rep. 2019. PMID: 31825838 Free PMC article.
Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.
Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, Simpson TI, Tybulewicz VL, Wyllie DJ, Fisher EM, Lowell S, Chandran S, Hardingham GE. Qiu J, et al. Among authors: mcqueen j. Elife. 2016 Oct 1;5:e20337. doi: 10.7554/eLife.20337. Elife. 2016. PMID: 27692071 Free PMC article.
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.
Hasel P, Dando O, Jiwaji Z, Baxter P, Todd AC, Heron S, Márkus NM, McQueen J, Hampton DW, Torvell M, Tiwari SS, McKay S, Eraso-Pichot A, Zorzano A, Masgrau R, Galea E, Chandran S, Wyllie DJA, Simpson TI, Hardingham GE. Hasel P, et al. Among authors: mcqueen j. Nat Commun. 2017 May 2;8:15132. doi: 10.1038/ncomms15132. Nat Commun. 2017. PMID: 28462931 Free PMC article.
Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.
Fowler JH, McQueen J, Holland PR, Manso Y, Marangoni M, Scott F, Chisholm E, Scannevin RH, Hardingham GE, Horsburgh K. Fowler JH, et al. Among authors: mcqueen j. J Cereb Blood Flow Metab. 2018 Aug;38(8):1354-1370. doi: 10.1177/0271678X17713105. Epub 2017 Jun 13. J Cereb Blood Flow Metab. 2018. PMID: 28606007 Free PMC article.
The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.
McKay S, Ryan TJ, McQueen J, Indersmitten T, Marwick KFM, Hasel P, Kopanitsa MV, Baxter PS, Martel MA, Kind PC, Wyllie DJA, O'Dell TJ, Grant SGN, Hardingham GE, Komiyama NH. McKay S, et al. Among authors: mcqueen j. Cell Rep. 2018 Oct 23;25(4):841-851.e4. doi: 10.1016/j.celrep.2018.09.089. Cell Rep. 2018. PMID: 30355491 Free PMC article.
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Jiwaji Z, Tiwari SS, Avilés-Reyes RX, Hooley M, Hampton D, Torvell M, Johnson DA, McQueen J, Baxter P, Sabari-Sankar K, Qiu J, He X, Fowler J, Febery J, Gregory J, Rose J, Tulloch J, Loan J, Story D, McDade K, Smith AM, Greer P, Ball M, Kind PC, Matthews PM, Smith C, Dando O, Spires-Jones TL, Johnson JA, Chandran S, Hardingham GE. Jiwaji Z, et al. Among authors: mcqueen j. Nat Commun. 2022 Jan 10;13(1):135. doi: 10.1038/s41467-021-27702-w. Nat Commun. 2022. PMID: 35013236 Free PMC article.
Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10+16 mutation.
Dando O, McGeachan R, McQueen J, Baxter P, Rockley N, McAlister H, Prasad A, He X, King D, Rose J, Jones PB, Tulloch J, Chandran S, Smith C, Hardingham G, Spires-Jones TL. Dando O, et al. Among authors: mcqueen j. medRxiv [Preprint]. 2024 Apr 12:2024.04.09.24305501. doi: 10.1101/2024.04.09.24305501. medRxiv. 2024. PMID: 38645146 Free PMC article. Preprint.
316 results