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Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques.
Pereira LE, Singletary T, Martin A, Dinh CT, Deyounks F, Holder A, McNicholl J, Buckheit KW, Buckheit RW Jr, Ham A, Katz DF, Smith JM. Pereira LE, et al. Among authors: mcnicholl j. Drug Deliv Transl Res. 2018 Oct;8(5):1180-1190. doi: 10.1007/s13346-018-0538-0. Drug Deliv Transl Res. 2018. PMID: 29761350 Free PMC article.
Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques.
Pereira LE, Mesquita PM, Ham A, Singletary T, Deyounks F, Martin A, McNicholl J, Buckheit KW, Buckheit RW Jr, Smith JM. Pereira LE, et al. Among authors: mcnicholl j. Antimicrob Agents Chemother. 2015 Dec 14;60(3):1393-400. doi: 10.1128/AAC.02201-15. Antimicrob Agents Chemother. 2015. PMID: 26666935 Free PMC article.
Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures.
Srinivasan P, Moss JA, Gunawardana M, Churchman SA, Yang F, Dinh CT, Mitchell JM, Zhang J, Fanter R, Miller CS, Butkyavichene I, McNicholl JM, Smith TJ, Baum MM, Smith JM. Srinivasan P, et al. Among authors: mcnicholl jm. PLoS One. 2016 Jun 8;11(6):e0157061. doi: 10.1371/journal.pone.0157061. eCollection 2016. PLoS One. 2016. PMID: 27275923 Free PMC article.
Combination Emtricitabine and Tenofovir Disoproxil Fumarate Prevents Vaginal Simian/Human Immunodeficiency Virus Infection in Macaques Harboring Chlamydia trachomatis and Trichomonas vaginalis.
Radzio J, Henning T, Jenkins L, Ellis S, Farshy C, Phillips C, Holder A, Kuklenyik S, Dinh C, Hanson D, McNicholl J, Heneine W, Papp J, Kersh EN, García-Lerma JG. Radzio J, et al. Among authors: mcnicholl j. J Infect Dis. 2016 May 15;213(10):1541-5. doi: 10.1093/infdis/jiw002. Epub 2016 Jan 6. J Infect Dis. 2016. PMID: 26743846 Free PMC article.
166 results