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An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease.
Wells JM, O'Reilly PJ, Szul T, Sullivan DI, Handley G, Garrett C, McNicholas CM, Roda MA, Miller BE, Tal-Singer R, Gaggar A, Rennard SI, Jackson PL, Blalock JE. Wells JM, et al. Among authors: mcnicholas cm. Am J Respir Crit Care Med. 2014 Jul 1;190(1):51-61. doi: 10.1164/rccm.201401-0145OC. Am J Respir Crit Care Med. 2014. PMID: 24874071 Free PMC article. Clinical Trial.
Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-induced Emphysema.
Roda MA, Xu X, Abdalla TH, Sadik M, Szul T, Bratcher PE, Viera L, Solomon GM, Wells JM, McNicholas CM, Redegeld FA, Folkerts G, Blalock JE, Gaggar A. Roda MA, et al. Among authors: mcnicholas cm. Am J Respir Cell Mol Biol. 2019 Nov;61(5):560-566. doi: 10.1165/rcmb.2018-0216OC. Am J Respir Cell Mol Biol. 2019. PMID: 30958968 Free PMC article.
Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function.
Raju SV, Jackson PL, Courville CA, McNicholas CM, Sloane PA, Sabbatini G, Tidwell S, Tang LP, Liu B, Fortenberry JA, Jones CW, Boydston JA, Clancy JP, Bowen LE, Accurso FJ, Blalock JE, Dransfield MT, Rowe SM. Raju SV, et al. Among authors: mcnicholas cm. Am J Respir Crit Care Med. 2013 Dec 1;188(11):1321-30. doi: 10.1164/rccm.201304-0733OC. Am J Respir Crit Care Med. 2013. PMID: 24040746 Free PMC article.
Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.
Genschmer KR, Russell DW, Lal C, Szul T, Bratcher PE, Noerager BD, Abdul Roda M, Xu X, Rezonzew G, Viera L, Dobosh BS, Margaroli C, Abdalla TH, King RW, McNicholas CM, Wells JM, Dransfield MT, Tirouvanziam R, Gaggar A, Blalock JE. Genschmer KR, et al. Among authors: mcnicholas cm. Cell. 2019 Jan 10;176(1-2):113-126.e15. doi: 10.1016/j.cell.2018.12.002. Cell. 2019. PMID: 30633902 Free PMC article.
The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke.
Raju SV, Lin VY, Liu L, McNicholas CM, Karki S, Sloane PA, Tang L, Jackson PL, Wang W, Wilson L, Macon KJ, Mazur M, Kappes JC, DeLucas LJ, Barnes S, Kirk K, Tearney GJ, Rowe SM. Raju SV, et al. Among authors: mcnicholas cm. Am J Respir Cell Mol Biol. 2017 Jan;56(1):99-108. doi: 10.1165/rcmb.2016-0226OC. Am J Respir Cell Mol Biol. 2017. PMID: 27585394 Free PMC article.
Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis.
Lambert JA, Raju SV, Tang LP, McNicholas CM, Li Y, Courville CA, Farris RF, Coricor GE, Smoot LH, Mazur MM, Dransfield MT, Bolger GB, Rowe SM. Lambert JA, et al. Among authors: mcnicholas cm. Am J Respir Cell Mol Biol. 2014 Mar;50(3):549-58. doi: 10.1165/rcmb.2013-0228OC. Am J Respir Cell Mol Biol. 2014. PMID: 24106801 Free PMC article.
34 results