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Cell-specific aptamers for targeted therapies.
Cerchia L, Giangrande PH, McNamara JO, de Franciscis V. Cerchia L, et al. Among authors: mcnamara jo. Methods Mol Biol. 2009;535:59-78. doi: 10.1007/978-1-59745-557-2_5. Methods Mol Biol. 2009. PMID: 19377980 Free PMC article. Review.
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras.
McNamara JO 2nd, Andrechek ER, Wang Y, Viles KD, Rempel RE, Gilboa E, Sullenger BA, Giangrande PH. McNamara JO 2nd, et al. Nat Biotechnol. 2006 Aug;24(8):1005-15. doi: 10.1038/nbt1223. Epub 2006 Jun 25. Nat Biotechnol. 2006. PMID: 16823371
Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.
Thiel KW, Hernandez LI, Dassie JP, Thiel WH, Liu X, Stockdale KR, Rothman AM, Hernandez FJ, McNamara JO 2nd, Giangrande PH. Thiel KW, et al. Among authors: mcnamara jo 2nd. Nucleic Acids Res. 2012 Jul;40(13):6319-37. doi: 10.1093/nar/gks294. Epub 2012 Mar 30. Nucleic Acids Res. 2012. PMID: 22467215 Free PMC article.
RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB.
Huang YZ, Hernandez FJ, Gu B, Stockdale KR, Nanapaneni K, Scheetz TE, Behlke MA, Peek AS, Bair T, Giangrande PH, McNamara JO 2nd. Huang YZ, et al. Among authors: mcnamara jo 2nd. Mol Pharmacol. 2012 Oct;82(4):623-35. doi: 10.1124/mol.112.078220. Epub 2012 Jun 29. Mol Pharmacol. 2012. PMID: 22752556 Free PMC article.
Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers.
Hernandez LI, Flenker KS, Hernandez FJ, Klingelhutz AJ, McNamara JO 2nd, Giangrande PH. Hernandez LI, et al. Among authors: mcnamara jo 2nd. Pharmaceuticals (Basel). 2013 Mar 14;6(3):295-319. doi: 10.3390/ph6030295. Pharmaceuticals (Basel). 2013. PMID: 23894227 Free PMC article.
Nucleotide bias observed with a short SELEX RNA aptamer library.
Thiel WH, Bair T, Wyatt Thiel K, Dassie JP, Rockey WM, Howell CA, Liu XY, Dupuy AJ, Huang L, Owczarzy R, Behlke MA, McNamara JO, Giangrande PH. Thiel WH, et al. Among authors: mcnamara jo. Nucleic Acid Ther. 2011 Aug;21(4):253-63. doi: 10.1089/nat.2011.0288. Epub 2011 Jun 28. Nucleic Acid Ther. 2011. PMID: 21793789 Free PMC article.
253 results