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Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes.
Ficarro SB, Browne CM, Card JD, Alexander WM, Zhang T, Park E, McNally R, Dhe-Paganon S, Seo HS, Lamberto I, Eck MJ, Buhrlage SJ, Gray NS, Marto JA. Ficarro SB, et al. Among authors: mcnally r. Anal Chem. 2016 Dec 20;88(24):12248-12254. doi: 10.1021/acs.analchem.6b03394. Epub 2016 Nov 30. Anal Chem. 2016. PMID: 28193034
Development of Selective Covalent Janus Kinase 3 Inhibitors.
Tan L, Akahane K, McNally R, Reyskens KM, Ficarro SB, Liu S, Herter-Sprie GS, Koyama S, Pattison MJ, Labella K, Johannessen L, Akbay EA, Wong KK, Frank DA, Marto JA, Look TA, Arthur JS, Eck MJ, Gray NS. Tan L, et al. Among authors: mcnally r. J Med Chem. 2015 Aug 27;58(16):6589-606. doi: 10.1021/acs.jmedchem.5b00710. Epub 2015 Aug 18. J Med Chem. 2015. PMID: 26258521 Free PMC article.
JAK-cytokine receptor recognition, unboxed.
McNally R, Eck MJ. McNally R, et al. Nat Struct Mol Biol. 2014 May;21(5):431-3. doi: 10.1038/nsmb.2824. Nat Struct Mol Biol. 2014. PMID: 24799036 No abstract available.
Crystal Structure of the FERM-SH2 Module of Human Jak2.
McNally R, Toms AV, Eck MJ. McNally R, et al. PLoS One. 2016 May 26;11(5):e0156218. doi: 10.1371/journal.pone.0156218. eCollection 2016. PLoS One. 2016. PMID: 27227461 Free PMC article.
560 results