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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein.
Albornoz EA, Amarilla AA, Modhiran N, Parker S, Li XX, Wijesundara DK, Aguado J, Zamora AP, McMillan CLD, Liang B, Peng NYG, Sng JDJ, Saima FT, Fung JN, Lee JD, Paramitha D, Parry R, Avumegah MS, Isaacs A, Lo MW, Miranda-Chacon Z, Bradshaw D, Salinas-Rebolledo C, Rajapakse NW, Wolvetang EJ, Munro TP, Rojas-Fernandez A, Young PR, Stacey KJ, Khromykh AA, Chappell KJ, Watterson D, Woodruff TM. Albornoz EA, et al. Among authors: mcmillan cld. Mol Psychiatry. 2023 Jul;28(7):2878-2893. doi: 10.1038/s41380-022-01831-0. Epub 2022 Nov 1. Mol Psychiatry. 2023. PMID: 36316366 Free PMC article.
A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2.
Xi CR, Di Fazio A, Nadvi NA, Patel K, Xiang MSW, Zhang HE, Deshpande C, Low JKK, Wang XT, Chen Y, McMillan CLD, Isaacs A, Osborne B, Vieira de Ribeiro AJ, McCaughan GW, Mackay JP, Church WB, Gorrell MD. Xi CR, et al. Among authors: mcmillan cld. Molecules. 2020 Nov 18;25(22):5392. doi: 10.3390/molecules25225392. Molecules. 2020. PMID: 33218025 Free PMC article.
Adjuvant Selection for Influenza and RSV Prefusion Subunit Vaccines.
Isaacs A, Li Z, Cheung STM, Wijesundara DK, McMillan CLD, Modhiran N, Young PR, Ranasinghe C, Watterson D, Chappell KJ. Isaacs A, et al. Among authors: mcmillan cld. Vaccines (Basel). 2021 Jan 20;9(2):71. doi: 10.3390/vaccines9020071. Vaccines (Basel). 2021. PMID: 33498370 Free PMC article.
An Optimized High-Throughput Immuno-Plaque Assay for SARS-CoV-2.
Amarilla AA, Modhiran N, Setoh YX, Peng NYG, Sng JDJ, Liang B, McMillan CLD, Freney ME, Cheung STM, Chappell KJ, Khromykh AA, Young PR, Watterson D. Amarilla AA, et al. Among authors: mcmillan cld. Front Microbiol. 2021 Feb 12;12:625136. doi: 10.3389/fmicb.2021.625136. eCollection 2021. Front Microbiol. 2021. PMID: 33643253 Free PMC article.
Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2.
Watterson D, Wijesundara DK, Modhiran N, Mordant FL, Li Z, Avumegah MS, McMillan CL, Lackenby J, Guilfoyle K, van Amerongen G, Stittelaar K, Cheung ST, Bibby S, Daleris M, Hoger K, Gillard M, Radunz E, Jones ML, Hughes K, Hughes B, Goh J, Edwards D, Scoble J, Pearce L, Kowalczyk L, Phan T, La M, Lu L, Pham T, Zhou Q, Brockman DA, Morgan SJ, Lau C, Tran MH, Tapley P, Villalón-Letelier F, Barnes J, Young A, Jaberolansar N, Scott CA, Isaacs A, Amarilla AA, Khromykh AA, van den Brand JM, Reading PC, Ranasinghe C, Subbarao K, Munro TP, Young PR, Chappell KJ. Watterson D, et al. Clin Transl Immunology. 2021 Apr 5;10(4):e1269. doi: 10.1002/cti2.1269. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33841880 Free PMC article.
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses.
Amarilla AA, Sng JDJ, Parry R, Deerain JM, Potter JR, Setoh YX, Rawle DJ, Le TT, Modhiran N, Wang X, Peng NYG, Torres FJ, Pyke A, Harrison JJ, Freney ME, Liang B, McMillan CLD, Cheung STM, Guevara DJDC, Hardy JM, Bettington M, Muller DA, Coulibaly F, Moore F, Hall RA, Young PR, Mackenzie JM, Hobson-Peters J, Suhrbier A, Watterson D, Khromykh AA. Amarilla AA, et al. Among authors: mcmillan cld. Nat Commun. 2021 Jun 8;12(1):3431. doi: 10.1038/s41467-021-23779-5. Nat Commun. 2021. PMID: 34103499 Free PMC article.
Complete protection by a single-dose skin patch-delivered SARS-CoV-2 spike vaccine.
McMillan CLD, Choo JJY, Idris A, Supramaniam A, Modhiran N, Amarilla AA, Isaacs A, Cheung STM, Liang B, Bielefeldt-Ohmann H, Azuar A, Acharya D, Kelly G, Fernando GJP, Landsberg MJ, Khromykh AA, Watterson D, Young PR, McMillan NAJ, Muller DA. McMillan CLD, et al. Among authors: mcmillan naj. Sci Adv. 2021 Oct 29;7(44):eabj8065. doi: 10.1126/sciadv.abj8065. Epub 2021 Oct 29. Sci Adv. 2021. PMID: 34714668 Free PMC article.
25 results