McManus M - Search Results

1

Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition.

Sharpley MS, Marciniak C, Eckel-Mahan K, McManus M, Crimi M, Waymire K, Lin CS, Masubuchi S, Friend N, Koike M, Chalkia D, MacGregor G, Sassone-Corsi P, Wallace DC. Sharpley MS, et al. Among authors: mcmanus m. Cell. 2012 Oct 12;151(2):333-343. doi: 10.1016/j.cell.2012.09.004. Cell. 2012. PMID: 23063123 Free PMC article.

2

Mouse mtDNA mutant model of Leber hereditary optic neuropathy.

Lin CS, Sharpley MS, Fan W, Waymire KG, Sadun AA, Carelli V, Ross-Cisneros FN, Baciu P, Sung E, McManus MJ, Pan BX, Gil DW, Macgregor GR, Wallace DC. Lin CS, et al. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20065-70. doi: 10.1073/pnas.1217113109. Epub 2012 Nov 5. Proc Natl Acad Sci U S A. 2012. PMID: 23129651 Free PMC article.

3

Differential Mitochondrial Requirements for Radially and Non-radially Migrating Cortical Neurons: Implications for Mitochondrial Disorders.

Lin-Hendel EG, McManus MJ, Wallace DC, Anderson SA, Golden JA. Lin-Hendel EG, et al. Cell Rep. 2016 Apr 12;15(2):229-37. doi: 10.1016/j.celrep.2016.03.024. Epub 2016 Mar 31. Cell Rep. 2016. PMID: 27050514 Free PMC article.

4

Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy.

McManus MJ, Picard M, Chen HW, De Haas HJ, Potluri P, Leipzig J, Towheed A, Angelin A, Sengupta P, Morrow RM, Kauffman BA, Vermulst M, Narula J, Wallace DC. McManus MJ, et al. Cell Metab. 2019 Jan 8;29(1):78-90.e5. doi: 10.1016/j.cmet.2018.08.002. Epub 2018 Aug 30. Cell Metab. 2019. PMID: 30174309 Free PMC article.

5

An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes.

Yardeni T, Cristancho AG, McCoy AJ, Schaefer PM, McManus MJ, Marsh ED, Wallace DC. Yardeni T, et al. Among authors: mcmanus mj. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2021429118. doi: 10.1073/pnas.2021429118. Proc Natl Acad Sci U S A. 2021. PMID: 33536343 Free PMC article.

6

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress.

Picard M, McManus MJ, Gray JD, Nasca C, Moffat C, Kopinski PK, Seifert EL, McEwen BS, Wallace DC. Picard M, et al. Among authors: mcmanus mj. Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):E6614-23. doi: 10.1073/pnas.1515733112. Epub 2015 Nov 16. Proc Natl Acad Sci U S A. 2015. PMID: 26627253 Free PMC article.

7

Trans-mitochondrial coordination of cristae at regulated membrane junctions.

Picard M, McManus MJ, Csordás G, Várnai P, Dorn GW 2nd, Williams D, Hajnóczky G, Wallace DC. Picard M, et al. Among authors: mcmanus mj. Nat Commun. 2015 Feb 17;6:6259. doi: 10.1038/ncomms7259. Nat Commun. 2015. PMID: 25687472 Free PMC article.

8

An X-chromosome linked mouse model (Ndufa1^S55A) for systemic partial Complex I deficiency for studying predisposition to neurodegeneration and other diseases.

Kim C, Potluri P, Khalil A, Gaut D, McManus M, Compton S, Wallace DC, Yadava N. Kim C, et al. Among authors: mcmanus m. Neurochem Int. 2017 Oct;109:78-93. doi: 10.1016/j.neuint.2017.05.003. Epub 2017 May 12. Neurochem Int. 2017. PMID: 28506826 Free article.

9

Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle.

Picard M, Gentil BJ, McManus MJ, White K, St Louis K, Gartside SE, Wallace DC, Turnbull DM. Picard M, et al. Among authors: mcmanus mj. J Appl Physiol (1985). 2013 Nov;115(10):1562-71. doi: 10.1152/japplphysiol.00819.2013. Epub 2013 Aug 22. J Appl Physiol (1985). 2013. PMID: 23970537 Free PMC article.

10

Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.

Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC. Morrow RM, et al. Among authors: mcmanus mj. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2705-2710. doi: 10.1073/pnas.1700997114. Epub 2017 Feb 21. Proc Natl Acad Sci U S A. 2017. PMID: 28223503 Free PMC article.

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