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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component.
O'Keefe BR, Vojdani F, Buffa V, Shattock RJ, Montefiori DC, Bakke J, Mirsalis J, d'Andrea AL, Hume SD, Bratcher B, Saucedo CJ, McMahon JB, Pogue GP, Palmer KE. O'Keefe BR, et al. Among authors: mcmahon jb. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6099-104. doi: 10.1073/pnas.0901506106. Epub 2009 Mar 30. Proc Natl Acad Sci U S A. 2009. PMID: 19332801 Free PMC article.
Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.
O'Keefe BR, Beutler JA, Cardellina JH 2nd, Gulakowski RJ, Krepps BL, McMahon JB, Sowder RC 2nd, Henderson LE, Pannell LK, Pomponi SA, Boyd MR. O'Keefe BR, et al. Among authors: mcmahon jb. Eur J Biochem. 1997 Apr 1;245(1):47-53. doi: 10.1111/j.1432-1033.1997.t01-1-00047.x. Eur J Biochem. 1997. PMID: 9128723 Free article.
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.
Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE. Boyd MR, et al. Among authors: mcmahon jb. Antimicrob Agents Chemother. 1997 Jul;41(7):1521-30. doi: 10.1128/AAC.41.7.1521. Antimicrob Agents Chemother. 1997. PMID: 9210678 Free PMC article.
156 results