McLean PJ - Search Results

1

14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein.

Wang B, Underwood R, Kamath A, Britain C, McFerrin MB, McLean PJ, Volpicelli-Daley LA, Whitaker RH, Placzek WJ, Becker K, Ma J, Yacoubian TA. Wang B, et al. Among authors: mclean pj. J Neurosci. 2018 Sep 19;38(38):8211-8232. doi: 10.1523/JNEUROSCI.1134-18.2018. Epub 2018 Aug 9. J Neurosci. 2018. PMID: 30093536 Free PMC article.

2

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.

McLean PJ, Kawamata H, Hyman BT. McLean PJ, et al. Neuroscience. 2001;104(3):901-12. doi: 10.1016/s0306-4522(01)00113-0. Neuroscience. 2001. PMID: 11440819

3

An alternatively spliced form of rodent alpha-synuclein forms intracellular inclusions in vitro: role of the carboxy-terminus in alpha-synuclein aggregation.

McLean PJ, Hyman BT. McLean PJ, et al. Neurosci Lett. 2002 May 3;323(3):219-23. doi: 10.1016/s0304-3940(02)00154-4. Neurosci Lett. 2002. PMID: 11959424

4

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation.

McLean PJ, Kawamata H, Shariff S, Hewett J, Sharma N, Ueda K, Breakefield XO, Hyman BT. McLean PJ, et al. J Neurochem. 2002 Nov;83(4):846-54. doi: 10.1046/j.1471-4159.2002.01190.x. J Neurochem. 2002. PMID: 12421356 Free article.

5

Transcriptional dysregulation in a transgenic model of Parkinson disease.

Yacoubian TA, Cantuti-Castelvetri I, Bouzou B, Asteris G, McLean PJ, Hyman BT, Standaert DG. Yacoubian TA, et al. Among authors: mclean pj. Neurobiol Dis. 2008 Mar;29(3):515-28. doi: 10.1016/j.nbd.2007.11.008. Epub 2007 Nov 28. Neurobiol Dis. 2008. PMID: 18191405 Free PMC article.

6

Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease.

Theodore S, Cao S, McLean PJ, Standaert DG. Theodore S, et al. Among authors: mclean pj. J Neuropathol Exp Neurol. 2008 Dec;67(12):1149-58. doi: 10.1097/NEN.0b013e31818e5e99. J Neuropathol Exp Neurol. 2008. PMID: 19018246 Free PMC article.

7

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies.

Mazzulli JR, Xu YH, Sun Y, Knight AL, McLean PJ, Caldwell GA, Sidransky E, Grabowski GA, Krainc D. Mazzulli JR, et al. Among authors: mclean pj. Cell. 2011 Jul 8;146(1):37-52. doi: 10.1016/j.cell.2011.06.001. Epub 2011 Jun 23. Cell. 2011. PMID: 21700325 Free PMC article.

8

Drug targets from genetics: α-synuclein.

Danzer KM, McLean PJ. Danzer KM, et al. Among authors: mclean pj. CNS Neurol Disord Drug Targets. 2011 Sep 1;10(6):712-23. doi: 10.2174/187152711797247867. CNS Neurol Disord Drug Targets. 2011. PMID: 21838671 Free PMC article. Review.

9

Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.

Ebrahimi-Fakhari D, Cantuti-Castelvetri I, Fan Z, Rockenstein E, Masliah E, Hyman BT, McLean PJ, Unni VK. Ebrahimi-Fakhari D, et al. Among authors: mclean pj. J Neurosci. 2011 Oct 12;31(41):14508-20. doi: 10.1523/JNEUROSCI.1560-11.2011. J Neurosci. 2011. PMID: 21994367 Free PMC article.

10

SIRT1 protects against α-synuclein aggregation by activating molecular chaperones.

Donmez G, Arun A, Chung CY, McLean PJ, Lindquist S, Guarente L. Donmez G, et al. Among authors: mclean pj. J Neurosci. 2012 Jan 4;32(1):124-32. doi: 10.1523/JNEUROSCI.3442-11.2012. J Neurosci. 2012. PMID: 22219275 Free PMC article. Retracted.

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