McLaughlin SH - Search Results

1

SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses.

Carnell GW, Ciazynska KA, Wells DA, Xiong X, Aguinam ET, McLaughlin SH, Mallery D, Ebrahimi S, Ceron-Gutierrez L, Asbach B, Einhauser S, Wagner R, James LC, Doffinger R, Heeney JL, Briggs JAG. Carnell GW, et al. Among authors: mclaughlin sh. J Virol. 2021 Jul 12;95(15):e0020321. doi: 10.1128/JVI.00203-21. Epub 2021 Jul 12. J Virol. 2021. PMID: 33963055 Free PMC article.

2

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.

Dickson C, Fletcher AJ, Vaysburd M, Yang JC, Mallery DL, Zeng J, Johnson CM, McLaughlin SH, Skehel M, Maslen S, Cruickshank J, Huguenin-Dezot N, Chin JW, Neuhaus D, James LC. Dickson C, et al. Among authors: mclaughlin sh. Elife. 2018 Apr 18;7:e32660. doi: 10.7554/eLife.32660. Elife. 2018. PMID: 29667579 Free PMC article.

3

A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.

Kiss L, Zeng J, Dickson CF, Mallery DL, Yang JC, McLaughlin SH, Boland A, Neuhaus D, James LC. Kiss L, et al. Among authors: mclaughlin sh. Nat Commun. 2019 Oct 3;10(1):4502. doi: 10.1038/s41467-019-12388-y. Nat Commun. 2019. PMID: 31582740 Free PMC article.

4

Target-induced clustering activates Trim-Away of pathogens and proteins.

Zeng J, Santos AF, Mukadam AS, Osswald M, Jacques DA, Dickson CF, McLaughlin SH, Johnson CM, Kiss L, Luptak J, Renner N, Vaysburd M, McEwan WA, Morais-de-Sá E, Clift D, James LC. Zeng J, et al. Among authors: mclaughlin sh. Nat Struct Mol Biol. 2021 Mar;28(3):278-289. doi: 10.1038/s41594-021-00560-2. Epub 2021 Feb 25. Nat Struct Mol Biol. 2021. PMID: 33633400 Free PMC article.

5

RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs.

McClintock MA, Dix CI, Johnson CM, McLaughlin SH, Maizels RJ, Hoang HT, Bullock SL. McClintock MA, et al. Among authors: mclaughlin sh. Elife. 2018 Jun 26;7:e36312. doi: 10.7554/eLife.36312. Elife. 2018. PMID: 29944118 Free PMC article.

6

An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.

Perera LA, Rato C, Yan Y, Neidhardt L, McLaughlin SH, Read RJ, Preissler S, Ron D. Perera LA, et al. Among authors: mclaughlin sh. EMBO J. 2019 Oct 4;38(21):e102177. doi: 10.15252/embj.2019102177. Epub 2019 Sep 18. EMBO J. 2019. PMID: 31531998 Free PMC article.

7

Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.

Chang L, Yang J, Jo CH, Boland A, Zhang Z, McLaughlin SH, Abu-Thuraia A, Killoran RC, Smith MJ, Côté JF, Barford D. Chang L, et al. Among authors: mclaughlin sh. Nat Commun. 2020 Jul 10;11(1):3464. doi: 10.1038/s41467-020-17271-9. Nat Commun. 2020. PMID: 32651375 Free PMC article.

8

Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.

Heimhalt M, Berndt A, Wagstaff J, Anandapadamanaban M, Perisic O, Maslen S, McLaughlin S, Yu CW, Masson GR, Boland A, Ni X, Yamashita K, Murshudov GN, Skehel M, Freund SM, Williams RL. Heimhalt M, et al. Elife. 2021 Sep 14;10:e68799. doi: 10.7554/eLife.68799. Elife. 2021. PMID: 34519269 Free PMC article.

9

The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.

Al-Jassar C, Andreeva A, Barnabas DD, McLaughlin SH, Johnson CM, Yu M, van Breugel M. Al-Jassar C, et al. Among authors: mclaughlin sh. Structure. 2017 Jan 3;25(1):146-156. doi: 10.1016/j.str.2016.11.014. Epub 2016 Dec 22. Structure. 2017. PMID: 28017521 Free PMC article.

10

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

Liu Y, Gupta GD, Barnabas DD, Agircan FG, Mehmood S, Wu D, Coyaud E, Johnson CM, McLaughlin SH, Andreeva A, Freund SMV, Robinson CV, Cheung SWT, Raught B, Pelletier L, van Breugel M. Liu Y, et al. Among authors: mclaughlin sh. Nat Commun. 2018 Apr 30;9(1):1731. doi: 10.1038/s41467-018-04122-x. Nat Commun. 2018. PMID: 29712910 Free PMC article.

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