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Page 1
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model.
Chen YA, Kankel MW, Hana S, Lau SK, Zavodszky MI, McKissick O, Mastrangelo N, Dion J, Wang B, Ferretti D, Koske D, Lehman S, Koszka K, McLaughlin H, Liu M, Marshall E, Fabian AJ, Cullen P, Marsh G, Hamann S, Craft M, Sebalusky J, Arnold HM, Driscoll R, Sheehy A, Luo Y, Manca S, Carlile T, Sun C, Sigrist K, McCampbell A, Henderson CE, Lo SC. Chen YA, et al. Among authors: mckissick o. Gene Ther. 2023 May;30(5):443-454. doi: 10.1038/s41434-022-00375-w. Epub 2022 Dec 1. Gene Ther. 2023. PMID: 36450833 Free PMC article.
Hippocampal cells segregate positive and negative engrams.
Shpokayte M, McKissick O, Guan X, Yuan B, Rahsepar B, Fernandez FR, Ruesch E, Grella SL, White JA, Liu XS, Ramirez S. Shpokayte M, et al. Among authors: mckissick o. Commun Biol. 2022 Sep 26;5(1):1009. doi: 10.1038/s42003-022-03906-8. Commun Biol. 2022. PMID: 36163262 Free PMC article.
Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice.
Hana S, Peterson M, McLaughlin H, Marshall E, Fabian AJ, McKissick O, Koszka K, Marsh G, Craft M, Xu S, Sorets A, Torregrosa T, Sun C, Henderson CE, Lo SC. Hana S, et al. Among authors: mckissick o. Gene Ther. 2021 Nov;28(10-11):646-658. doi: 10.1038/s41434-021-00224-2. Epub 2021 Feb 8. Gene Ther. 2021. PMID: 33558692 Free PMC article.
Odor modulates the temporal dynamics of fear memory consolidation.
Grella SL, Fortin AH, McKissick O, Leblanc H, Ramirez S. Grella SL, et al. Among authors: mckissick o. Learn Mem. 2020 Mar 16;27(4):150-163. doi: 10.1101/lm.050690.119. Print 2020 Apr. Learn Mem. 2020. PMID: 32179657 Free PMC article.
Artificially Enhancing and Suppressing Hippocampus-Mediated Memories.
Chen BK, Murawski NJ, Cincotta C, McKissick O, Finkelstein A, Hamidi AB, Merfeld E, Doucette E, Grella SL, Shpokayte M, Zaki Y, Fortin A, Ramirez S. Chen BK, et al. Among authors: mckissick o. Curr Biol. 2019 Jun 3;29(11):1885-1894.e4. doi: 10.1016/j.cub.2019.04.065. Epub 2019 May 23. Curr Biol. 2019. PMID: 31130452 Free PMC article.