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Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.
Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA. Stratton MS, et al. Among authors: mckinsey ta. Circ Res. 2019 Sep 13;125(7):662-677. doi: 10.1161/CIRCRESAHA.119.315125. Epub 2019 Aug 14. Circ Res. 2019. PMID: 31409188 Free PMC article.
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Lemon DD, et al. Among authors: mckinsey ta. J Mol Cell Cardiol. 2011 Jul;51(1):41-50. doi: 10.1016/j.yjmcc.2011.04.005. Epub 2011 Apr 23. J Mol Cell Cardiol. 2011. PMID: 21539845 Free PMC article.
Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. Cavasin MA, et al. Among authors: mckinsey ta. Circ Res. 2012 Mar 2;110(5):739-48. doi: 10.1161/CIRCRESAHA.111.258426. Epub 2012 Jan 26. Circ Res. 2012. PMID: 22282194 Free PMC article.
BET acetyl-lysine binding proteins control pathological cardiac hypertrophy.
Spiltoir JI, Stratton MS, Cavasin MA, Demos-Davies K, Reid BG, Qi J, Bradner JE, McKinsey TA. Spiltoir JI, et al. Among authors: mckinsey ta. J Mol Cell Cardiol. 2013 Oct;63:175-9. doi: 10.1016/j.yjmcc.2013.07.017. Epub 2013 Aug 9. J Mol Cell Cardiol. 2013. PMID: 23939492 Free PMC article.
MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
Wang D, Zhang H, Li M, Frid MG, Flockton AR, McKeon BA, Yeager ME, Fini MA, Morrell NW, Pullamsetti SS, Velegala S, Seeger W, McKinsey TA, Sucharov CC, Stenmark KR. Wang D, et al. Among authors: mckinsey ta. Circ Res. 2014 Jan 3;114(1):67-78. doi: 10.1161/CIRCRESAHA.114.301633. Epub 2013 Oct 11. Circ Res. 2014. PMID: 24122720 Free PMC article.
BET-ting on chromatin-based therapeutics for heart failure.
Haldar SM, McKinsey TA. Haldar SM, et al. Among authors: mckinsey ta. J Mol Cell Cardiol. 2014 Sep;74:98-102. doi: 10.1016/j.yjmcc.2014.05.002. Epub 2014 May 14. J Mol Cell Cardiol. 2014. PMID: 24838003 Free PMC article. Review.
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Demos-Davies KM, Ferguson BS, Cavasin MA, Mahaffey JH, Williams SM, Spiltoir JI, Schuetze KB, Horn TR, Chen B, Ferrara C, Scellini B, Piroddi N, Tesi C, Poggesi C, Jeong MY, McKinsey TA. Demos-Davies KM, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H252-8. doi: 10.1152/ajpheart.00149.2014. Epub 2014 May 23. Am J Physiol Heart Circ Physiol. 2014. PMID: 24858848 Free PMC article.
183 results