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Page 1
Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.
Li M, Riddle SR, Frid MG, El Kasmi KC, McKinsey TA, Sokol RJ, Strassheim D, Meyrick B, Yeager ME, Flockton AR, McKeon BA, Lemon DD, Horn TR, Anwar A, Barajas C, Stenmark KR. Li M, et al. Among authors: mckeon ba. J Immunol. 2011 Sep 1;187(5):2711-22. doi: 10.4049/jimmunol.1100479. Epub 2011 Aug 3. J Immunol. 2011. PMID: 21813768 Free PMC article.
Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.
Anwar A, Li M, Frid MG, Kumar B, Gerasimovskaya EV, Riddle SR, McKeon BA, Thukaram R, Meyrick BO, Fini MA, Stenmark KR. Anwar A, et al. Among authors: mckeon ba. Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L1-L11. doi: 10.1152/ajplung.00050.2012. Epub 2012 May 11. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22582113 Free PMC article.
MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
Wang D, Zhang H, Li M, Frid MG, Flockton AR, McKeon BA, Yeager ME, Fini MA, Morrell NW, Pullamsetti SS, Velegala S, Seeger W, McKinsey TA, Sucharov CC, Stenmark KR. Wang D, et al. Among authors: mckeon ba. Circ Res. 2014 Jan 3;114(1):67-78. doi: 10.1161/CIRCRESAHA.114.301633. Epub 2013 Oct 11. Circ Res. 2014. PMID: 24122720 Free PMC article.
Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.
Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldovan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Ježek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR. Li M, et al. Among authors: mckeon ba. Circulation. 2016 Oct 11;134(15):1105-1121. doi: 10.1161/CIRCULATIONAHA.116.023171. Epub 2016 Aug 25. Circulation. 2016. PMID: 27562971 Free PMC article.
TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Kumar R, et al. Among authors: mckeon ba. Nat Commun. 2017 May 30;8:15494. doi: 10.1038/ncomms15494. Nat Commun. 2017. PMID: 28555642 Free PMC article.
Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton A, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Ježek P, Morrell NW, Hu CJ, Stenmark KR. Zhang H, et al. Among authors: mckeon ba. Circulation. 2017 Dec 19;136(25):2468-2485. doi: 10.1161/CIRCULATIONAHA.117.028069. Epub 2017 Sep 26. Circulation. 2017. PMID: 28972001 Free PMC article.
Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KR. Frid MG, et al. Among authors: mckeon ba. Am J Respir Crit Care Med. 2020 Jan 15;201(2):224-239. doi: 10.1164/rccm.201903-0591OC. Am J Respir Crit Care Med. 2020. PMID: 31545648 Free PMC article.
Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.
Li M, Riddle S, Kumar S, Poczobutt J, McKeon BA, Frid MG, Ostaff M, Reisz JA, Nemkov T, Fini MA, Laux A, Hu CJ, El Kasmi KC, D'Alessandro A, Brown RD, Zhang H, Stenmark KR. Li M, et al. Among authors: mckeon ba. Front Immunol. 2021 Mar 31;12:640718. doi: 10.3389/fimmu.2021.640718. eCollection 2021. Front Immunol. 2021. PMID: 33868271 Free PMC article.
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