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Design, structure-activity relationship, and in vivo characterization of the development candidate NVP-HSP990.
McBride CM, Levine B, Xia Y, Bellamacina C, Machajewski T, Gao Z, Renhowe P, Antonios-McCrea W, Barsanti P, Brinner K, Costales A, Doughan B, Lin X, Louie A, McKenna M, Mendenhall K, Poon D, Rico A, Wang M, Williams TE, Abrams T, Fong S, Hendrickson T, Lei D, Lin J, Menezes D, Pryer N, Taverna P, Xu Y, Zhou Y, Shafer CM. McBride CM, et al. Among authors: mckenna m. J Med Chem. 2014 Nov 13;57(21):9124-9. doi: 10.1021/jm501107q. Epub 2014 Nov 4. J Med Chem. 2014. PMID: 25368984
Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma.
Williams TE, Subramanian S, Verhagen J, McBride CM, Costales A, Sung L, Antonios-McCrea W, McKenna M, Louie AK, Ramurthy S, Levine B, Shafer CM, Machajewski T, Renhowe PA, Appleton BA, Amiri P, Chou J, Stuart D, Aardalen K, Poon D. Williams TE, et al. Among authors: mckenna m. ACS Med Chem Lett. 2015 Aug 3;6(9):961-5. doi: 10.1021/ml500526p. eCollection 2015 Sep 10. ACS Med Chem Lett. 2015. PMID: 26396681 Free PMC article.
3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.
Lindvall M, McBride C, McKenna M, Gesner TG, Yabannavar A, Wong K, Lin S, Walter A, Shafer CM. Lindvall M, et al. Among authors: mckenna m. ACS Med Chem Lett. 2011 Aug 2;2(10):720-3. doi: 10.1021/ml200029w. eCollection 2011 Oct 13. ACS Med Chem Lett. 2011. PMID: 24900258 Free PMC article.
Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.
Lingel A, Sendzik M, Huang Y, Shultz MD, Cantwell J, Dillon MP, Fu X, Fuller J, Gabriel T, Gu J, Jiang X, Li L, Liang F, McKenna M, Qi W, Rao W, Sheng X, Shu W, Sutton J, Taft B, Wang L, Zeng J, Zhang H, Zhang M, Zhao K, Lindvall M, Bussiere DE. Lingel A, et al. Among authors: mckenna m. J Med Chem. 2017 Jan 12;60(1):415-427. doi: 10.1021/acs.jmedchem.6b01473. Epub 2017 Jan 3. J Med Chem. 2017. PMID: 27992714
A dual-luciferase bioluminescence system for the assessment of cellular therapies.
Torres Chavez AG, McKenna MK, Balasubramanian K, Riffle L, Patel NL, Kalen JD, St Croix B, Leen AM, Bajgain P. Torres Chavez AG, et al. Among authors: mckenna mk. Mol Ther Oncol. 2024 Jan 10;32(1):200763. doi: 10.1016/j.omton.2024.200763. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596291 Free PMC article.
Understanding vessel noise across a network of marine protected areas.
McKenna MF, Rowell TJ, Margolina T, Baumann-Pickering S, Solsona-Berga A, Adams JD, Joseph J, Kim EB, Kok AC, Kügler A, Lammers MO, Merkens K, Reeves LP, Southall BL, Stimpert AK, Barkowski J, Thompson MA, Van Parijs S, Wall CC, Zang EJ, Hatch LT. McKenna MF, et al. Environ Monit Assess. 2024 Mar 15;196(4):369. doi: 10.1007/s10661-024-12497-2. Environ Monit Assess. 2024. PMID: 38489113 Free PMC article.
1,160 results