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201 results

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Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial.
Rivellese F, Surace AEA, Goldmann K, Sciacca E, Çubuk C, Giorli G, John CR, Nerviani A, Fossati-Jimack L, Thorborn G, Ahmed M, Prediletto E, Church SE, Hudson BM, Warren SE, McKeigue PM, Humby F, Bombardieri M, Barnes MR, Lewis MJ, Pitzalis C; R4RA collaborative group. Rivellese F, et al. Among authors: mckeigue pm. Nat Med. 2022 Jun;28(6):1256-1268. doi: 10.1038/s41591-022-01789-0. Epub 2022 May 19. Nat Med. 2022. PMID: 35589854 Free PMC article. Clinical Trial.
Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.
Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M, Plant D, Colombo M, Orchard P, Twigg S, McInnes IB, Porter D, Freeston JE, Nam JL, Cordell HJ, Isaacs JD, Strathdee JL, Arnett D, de Hair MJH, Tak PP, Aslibekyan S, van Vollenhoven RF, Padyukov L, Bridges SL, Pitzalis C, Cope AP, Verstappen SMM, Emery P, Barnes MR, Agakov F, McKeigue P, Mushiroda T, Kubo M, Weinshilboum R, Barton A, Morgan AW, Barrett JH; MATURA; and PAMERA; Consortia. Taylor JC, et al. Pharmacogenomics J. 2018 Jul;18(4):528-538. doi: 10.1038/s41397-018-0025-5. Epub 2018 May 25. Pharmacogenomics J. 2018. PMID: 29795407 Free article. Review.
Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis.
Hensor EMA, McKeigue P, Ling SF, Colombo M, Barrett JH, Nam JL, Freeston J, Buch MH, Spiliopoulou A, Agakov F, Kelly S, Lewis MJ, Verstappen SMM, MacGregor AJ, Viatte S, Barton A, Pitzalis C, Emery P, Conaghan PG, Morgan AW. Hensor EMA, et al. Rheumatology (Oxford). 2019 Mar 1;58(8):1400-9. doi: 10.1093/rheumatology/kez049. Online ahead of print. Rheumatology (Oxford). 2019. PMID: 30824919 Free PMC article.
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39.
Spiliopoulou A, Colombo M, Plant D, Nair N, Cui J, Coenen MJ, Ikari K, Yamanaka H, Saevarsdottir S, Padyukov L, Bridges SL Jr, Kimberly RP, Okada Y, van Riel PLC, Wolbink G, van der Horst-Bruinsma IE, de Vries N, Tak PP, Ohmura K, Canhão H, Guchelaar HJ, Huizinga TW, Criswell LA, Raychaudhuri S, Weinblatt ME, Wilson AG, Mariette X, Isaacs JD, Morgan AW, Pitzalis C, Barton A, McKeigue P. Spiliopoulou A, et al. Ann Rheum Dis. 2019 Aug;78(8):1055-1061. doi: 10.1136/annrheumdis-2018-214877. Epub 2019 Apr 29. Ann Rheum Dis. 2019. PMID: 31036624 Free PMC article.
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response.
Cherlin S, Lewis MJ, Plant D, Nair N, Goldmann K, Tzanis E, Barnes MR, McKeigue P, Barrett JH, Pitzalis C, Barton A; MATURA Consortium; Cordell HJ. Cherlin S, et al. Ann Rheum Dis. 2020 Nov;79(11):1446-1452. doi: 10.1136/annrheumdis-2020-217204. Epub 2020 Jul 30. Ann Rheum Dis. 2020. PMID: 32732242 Free PMC article.
Malaria susceptibility and CD36 mutation.
Aitman TJ, Cooper LD, Norsworthy PJ, Wahid FN, Gray JK, Curtis BR, McKeigue PM, Kwiatkowski D, Greenwood BM, Snow RW, Hill AV, Scott J. Aitman TJ, et al. Among authors: mckeigue pm. Nature. 2000 Jun 29;405(6790):1015-6. doi: 10.1038/35016636. Nature. 2000. PMID: 10890433 No abstract available.
Abundant pleiotropy in human complex diseases and traits.
Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H. Sivakumaran S, et al. Am J Hum Genet. 2011 Nov 11;89(5):607-18. doi: 10.1016/j.ajhg.2011.10.004. Am J Hum Genet. 2011. PMID: 22077970 Free PMC article. Review.
201 results