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Metformin rescues muscle function in BAG3 myofibrillar myopathy models.
Autophagy. 2021 Sep;17(9):2494-2510. doi: 10.1080/15548627.2020.1833500. Epub 2020 Oct 19.
Autophagy. 2021.
PMID: 33030392
Free PMC article.
Genetic compensation triggered by actin mutation prevents the muscle damage caused by loss of actin protein.
Sztal TE, McKaige EA, Williams C, Ruparelia AA, Bryson-Richardson RJ.
Sztal TE, et al. Among authors: mckaige ea.
PLoS Genet. 2018 Feb 8;14(2):e1007212. doi: 10.1371/journal.pgen.1007212. eCollection 2018 Feb.
PLoS Genet. 2018.
PMID: 29420541
Free PMC article.
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Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy.
Sztal TE, McKaige EA, Williams C, Oorschot V, Ramm G, Bryson-Richardson RJ.
Sztal TE, et al. Among authors: mckaige ea.
Acta Neuropathol Commun. 2018 May 30;6(1):40. doi: 10.1186/s40478-018-0546-9.
Acta Neuropathol Commun. 2018.
PMID: 29848386
Free PMC article.
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RGD inhibition of itgb1 ameliorates laminin-α2-deficient zebrafish fibre pathology.
Wood AJ, Cohen N, Joshi V, Li M, Costin A, Hersey L, McKaige EA, Manneken JD, Sonntag C, Miles LB, Siegel A, Currie PD.
Wood AJ, et al. Among authors: mckaige ea.
Hum Mol Genet. 2019 May 1;28(9):1403-1413. doi: 10.1093/hmg/ddy426.
Hum Mol Genet. 2019.
PMID: 30566586
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Mitochondrial abnormalities contribute to muscle weakness in a Dnajb6 deficient zebrafish model.
McKaige EA, Lee C, Calcinotto V, Giri S, Crawford S, McGrath MJ, Ramm G, Bryson-Richardson RJ.
McKaige EA, et al.
Hum Mol Genet. 2024 Apr 15:ddae061. doi: 10.1093/hmg/ddae061. Online ahead of print.
Hum Mol Genet. 2024.
PMID: 38621658
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