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A Semimechanistic Pharmacokinetic Model for Depot Medroxyprogesterone Acetate and Drug-Drug Interactions With Antiretroviral and Antituberculosis Treatment.
Francis J, Mngqibisa R, McIlleron H, Kendall MA, Wu X, Dooley KE, Firnhaber C, Godfrey C, Cohn SE, Denti P; A5093, A5283, A5338 study teams. Francis J, et al. Among authors: mcilleron h. Clin Pharmacol Ther. 2021 Oct;110(4):1057-1065. doi: 10.1002/cpt.2324. Epub 2021 Jul 1. Clin Pharmacol Ther. 2021. PMID: 34151439 Free PMC article.
The SLCO1B1 rs4149032 polymorphism is highly prevalent in South Africans and is associated with reduced rifampin concentrations: dosing implications.
Chigutsa E, Visser ME, Swart EC, Denti P, Pushpakom S, Egan D, Holford NH, Smith PJ, Maartens G, Owen A, McIlleron H. Chigutsa E, et al. Among authors: mcilleron h. Antimicrob Agents Chemother. 2011 Sep;55(9):4122-7. doi: 10.1128/AAC.01833-10. Epub 2011 Jun 27. Antimicrob Agents Chemother. 2011. PMID: 21709081 Free PMC article.
A semimechanistic pharmacokinetic-enzyme turnover model for rifampin autoinduction in adult tuberculosis patients.
Smythe W, Khandelwal A, Merle C, Rustomjee R, Gninafon M, Bocar Lo M, Sow OB, Olliaro PL, Lienhardt C, Horton J, Smith P, McIlleron H, Simonsson US. Smythe W, et al. Among authors: mcilleron h. Antimicrob Agents Chemother. 2012 Apr;56(4):2091-8. doi: 10.1128/AAC.05792-11. Epub 2012 Jan 17. Antimicrob Agents Chemother. 2012. PMID: 22252827 Free PMC article. Clinical Trial.
204 results