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Polymersomes Eradicating Intracellular Bacteria.
Fenaroli F, Robertson JD, Scarpa E, Gouveia VM, Di Guglielmo C, De Pace C, Elks PM, Poma A, Evangelopoulos D, Canseco JO, Prajsnar TK, Marriott HM, Dockrell DH, Foster SJ, McHugh TD, Renshaw SA, Martí JS, Battaglia G, Rizzello L. Fenaroli F, et al. Among authors: mchugh td. ACS Nano. 2020 Jul 28;14(7):8287-8298. doi: 10.1021/acsnano.0c01870. Epub 2020 Jun 19. ACS Nano. 2020. PMID: 32515944 Free article.
ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents.
McGuigan C, Derudas M, Gonczy B, Hinsinger K, Kandil S, Pertusati F, Serpi M, Snoeck R, Andrei G, Balzarini J, McHugh TD, Maitra A, Akorli E, Evangelopoulos D, Bhakta S. McGuigan C, et al. Among authors: mchugh td. Bioorg Med Chem. 2014 May 1;22(9):2816-24. doi: 10.1016/j.bmc.2014.02.056. Epub 2014 Mar 15. Bioorg Med Chem. 2014. PMID: 24690527 Free article.
Effective anti-tuberculosis therapy correlates with plasma small RNA.
Honeyborne I, Lipman MC, Eckold C, Evangelopoulos D, Gillespie SH, Pym A, McHugh TD. Honeyborne I, et al. Among authors: mchugh td. Eur Respir J. 2015 Jun;45(6):1741-4. doi: 10.1183/09031936.00221214. Epub 2015 Mar 5. Eur Respir J. 2015. PMID: 25745052 Free article. No abstract available.
Improving the tuberculosis drug development pipeline.
Evangelopoulos D, McHugh TD. Evangelopoulos D, et al. Among authors: mchugh td. Chem Biol Drug Des. 2015 Nov;86(5):951-60. doi: 10.1111/cbdd.12549. Epub 2015 Mar 28. Chem Biol Drug Des. 2015. PMID: 25772393 Review.
Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercular Agents Effective against Multidrug-Resistant Mycobacteria.
Bhakta S, Scalacci N, Maitra A, Brown AK, Dasugari S, Evangelopoulos D, McHugh TD, Mortazavi PN, Twist A, Petricci E, Manetti F, Castagnolo D. Bhakta S, et al. Among authors: mchugh td. J Med Chem. 2016 Mar 24;59(6):2780-93. doi: 10.1021/acs.jmedchem.6b00031. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26907951 Free article.
234 results