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Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315.
Jeeves RE, Marriott AA, Pullan ST, Hatch KA, Allnutt JC, Freire-Martin I, Hendon-Dunn CL, Watson R, Witney AA, Tyler RH, Arnold C, Marsh PD, McHugh TD, Bacon J. Jeeves RE, et al. Among authors: mchugh td. PLoS One. 2015 Sep 18;10(9):e0138253. doi: 10.1371/journal.pone.0138253. eCollection 2015. PLoS One. 2015. PMID: 26382066 Free PMC article.
Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH.
Jenkins C, Bacon J, Allnutt J, Hatch KA, Bose A, O'Sullivan DM, Arnold C, Gillespie SH, McHugh TD. Jenkins C, et al. Among authors: mchugh td. J Antimicrob Chemother. 2009 Jun;63(6):1118-20. doi: 10.1093/jac/dkp125. Epub 2009 Apr 15. J Antimicrob Chemother. 2009. PMID: 19369270
Molecular bacterial load assay, a culture-free biomarker for rapid and accurate quantification of sputum Mycobacterium tuberculosis bacillary load during treatment.
Honeyborne I, McHugh TD, Phillips PP, Bannoo S, Bateson A, Carroll N, Perrin FM, Ronacher K, Wright L, van Helden PD, Walzl G, Gillespie SH. Honeyborne I, et al. Among authors: mchugh td. J Clin Microbiol. 2011 Nov;49(11):3905-11. doi: 10.1128/JCM.00547-11. Epub 2011 Sep 7. J Clin Microbiol. 2011. PMID: 21900522 Free PMC article.
Direct Whole-Genome Sequencing of Sputum Accurately Identifies Drug-Resistant Mycobacterium tuberculosis Faster than MGIT Culture Sequencing.
Doyle RM, Burgess C, Williams R, Gorton R, Booth H, Brown J, Bryant JM, Chan J, Creer D, Holdstock J, Kunst H, Lozewicz S, Platt G, Romero EY, Speight G, Tiberi S, Abubakar I, Lipman M, McHugh TD, Breuer J. Doyle RM, et al. Among authors: mchugh td. J Clin Microbiol. 2018 Jul 26;56(8):e00666-18. doi: 10.1128/JCM.00666-18. Print 2018 Aug. J Clin Microbiol. 2018. PMID: 29848567 Free PMC article.
234 results