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Phospholipase C epsilon suppresses integrin activation.
Lad Y, McHugh B, Hodkinson PS, Mackinnon AC, Haslett C, Ginsberg MH, Sethi T. Lad Y, et al. J Biol Chem. 2006 Oct 6;281(40):29501-12. doi: 10.1074/jbc.M513471200. Epub 2006 Aug 8. J Biol Chem. 2006. PMID: 16895916 Free article.
Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.
Hodkinson PS, Elliott PA, Lad Y, McHugh BJ, MacKinnon AC, Haslett C, Sethi T. Hodkinson PS, et al. Among authors: mchugh bj. J Biol Chem. 2007 Sep 28;282(39):28991-29001. doi: 10.1074/jbc.M703601200. Epub 2007 Jul 30. J Biol Chem. 2007. PMID: 17664272 Free article.
Blood Neutrophils Are Reprogrammed in Bronchiectasis.
Bedi P, Davidson DJ, McHugh BJ, Rossi AG, Hill AT. Bedi P, et al. Among authors: mchugh bj. Am J Respir Crit Care Med. 2018 Oct 1;198(7):880-890. doi: 10.1164/rccm.201712-2423OC. Am J Respir Crit Care Med. 2018. PMID: 29733693 Free PMC article.
Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa.
McHugh BJ, Wang R, Li HN, Beaumont PE, Kells R, Stevens H, Young L, Rossi AG, Gray RD, Dorin JR, Gwyer Findlay EL, Brough D, Davidson DJ. McHugh BJ, et al. PLoS Pathog. 2019 Apr 12;15(4):e1007694. doi: 10.1371/journal.ppat.1007694. eCollection 2019 Apr. PLoS Pathog. 2019. PMID: 30978238 Free PMC article.
Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation.
Humphries DC, Mills R, Boz C, McHugh BJ, Hirani N, Rossi AG, Pedersen A, Schambye HT, Slack RJ, Leffler H, Nilsson UJ, Wang W, Sethi T, Mackinnon AC. Humphries DC, et al. Among authors: mchugh bj. Front Pharmacol. 2022 Aug 8;13:949264. doi: 10.3389/fphar.2022.949264. eCollection 2022. Front Pharmacol. 2022. PMID: 36003515 Free PMC article.
Human cathelicidin production by the cervix.
Frew L, Makieva S, McKinlay AT, McHugh BJ, Doust A, Norman JE, Davidson DJ, Stock SJ. Frew L, et al. Among authors: mchugh bj. PLoS One. 2014 Aug 4;9(8):e103434. doi: 10.1371/journal.pone.0103434. eCollection 2014. PLoS One. 2014. PMID: 25089904 Free PMC article.
34 results