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Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
Bancroft T, DeBuysscher BL, Weidle C, Schwartz A, Wall A, Gray MD, Feng J, Steach HR, Fitzpatrick KS, Gewe MM, Skog PD, Doyle-Cooper C, Ota T, Strong RK, Nemazee D, Pancera M, Stamatatos L, McGuire AT, Taylor JJ. Bancroft T, et al. Among authors: mcguire at. J Exp Med. 2019 Oct 7;216(10):2331-2347. doi: 10.1084/jem.20190164. Epub 2019 Jul 25. J Exp Med. 2019. PMID: 31345930 Free PMC article. Clinical Trial.
Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
Dosenovic P, Pettersson AK, Wall A, Thientosapol ES, Feng J, Weidle C, Bhullar K, Kara EE, Hartweger H, Pai JA, Gray MD, Parks KR, Taylor JJ, Pancera M, Stamatatos L, Nussenzweig MC, McGuire AT. Dosenovic P, et al. Among authors: mcguire at. J Exp Med. 2019 Oct 7;216(10):2316-2330. doi: 10.1084/jem.20190446. Epub 2019 Jul 25. J Exp Med. 2019. PMID: 31345931 Free PMC article.
Generation of a cost-effective cell line for support of high-throughput isolation of primary human B cells and monoclonal neutralizing antibodies.
Whaley RE, Ameny S, Arkatkar T, Seese A, Wall A, Khan I, Carter JJ, Scherer EM, Rawlings DJ, Galloway DA, McElrath MJ, Cohen KW, McGuire AT. Whaley RE, et al. Among authors: mcguire at. J Immunol Methods. 2021 Jan;488:112901. doi: 10.1016/j.jim.2020.112901. Epub 2020 Oct 15. J Immunol Methods. 2021. PMID: 33069767 Free PMC article.
Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
Hurlburt NK, Homad LJ, Sinha I, Jennewein MF, MacCamy AJ, Wan YH, Boonyaratanakornkit J, Sholukh AM, Jackson AM, Zhou P, Burton DR, Andrabi R, Ozorowski G, Ward AB, Stamatatos L, Pancera M, McGuire AT. Hurlburt NK, et al. Among authors: mcguire at. Commun Biol. 2022 Apr 11;5(1):342. doi: 10.1038/s42003-022-03262-7. Commun Biol. 2022. PMID: 35411021 Free PMC article.
Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge.
Malhi H, Homad LJ, Wan YH, Poudel B, Fiala B, Borst AJ, Wang JY, Walkey C, Price J, Wall A, Singh S, Moodie Z, Carter L, Handa S, Correnti CE, Stoddard BL, Veesler D, Pancera M, Olson J, King NP, McGuire AT. Malhi H, et al. Among authors: mcguire at. Cell Rep Med. 2022 Jun 21;3(6):100658. doi: 10.1016/j.xcrm.2022.100658. Epub 2022 Jun 14. Cell Rep Med. 2022. PMID: 35705092 Free PMC article.
73 results