McGrail JC - Search Results

1

Exploiting a living biobank to delineate mechanisms underlying disease-specific chromosome instability.

Nelson L, Barnes BM, Tighe A, Littler S, Coulson-Gilmer C, Golder A, Desai S, Morgan RD, McGrail JC, Taylor SS. Nelson L, et al. Among authors: mcgrail jc. Chromosome Res. 2023 Aug 17;31(3):21. doi: 10.1007/s10577-023-09731-x. Chromosome Res. 2023. PMID: 37592171 Free PMC article. Review.

2

Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes.

Barnes BM, Nelson L, Tighe A, Burghel GJ, Lin IH, Desai S, McGrail JC, Morgan RD, Taylor SS. Barnes BM, et al. Among authors: mcgrail jc. Genome Med. 2021 Sep 1;13(1):140. doi: 10.1186/s13073-021-00952-5. Genome Med. 2021. PMID: 34470661 Free PMC article.

3

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells.

Bronder D, Tighe A, Wangsa D, Zong D, Meyer TJ, Wardenaar R, Minshall P, Hirsch D, Heselmeyer-Haddad K, Nelson L, Spierings D, McGrail JC, Cam M, Nussenzweig A, Foijer F, Ried T, Taylor SS. Bronder D, et al. Among authors: mcgrail jc. Dis Model Mech. 2021 Nov 1;14(11):dmm049001. doi: 10.1242/dmm.049001. Epub 2021 Nov 30. Dis Model Mech. 2021. PMID: 34569598 Free PMC article.

4

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models.

Coulson-Gilmer C, Morgan RD, Nelson L, Barnes BM, Tighe A, Wardenaar R, Spierings DCJ, Schlecht H, Burghel GJ, Foijer F, Desai S, McGrail JC, Taylor SS. Coulson-Gilmer C, et al. Among authors: mcgrail jc. J Exp Clin Cancer Res. 2021 Oct 16;40(1):323. doi: 10.1186/s13046-021-02124-0. J Exp Clin Cancer Res. 2021. PMID: 34656146 Free PMC article.

5

Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors.

Golder A, Nelson L, Tighe A, Barnes B, Coulson-Gilmer C, Morgan RD, McGrail JC, Taylor SS. Golder A, et al. Among authors: mcgrail jc. NAR Cancer. 2022 Nov 12;4(4):zcac036. doi: 10.1093/narcan/zcac036. eCollection 2022 Dec. NAR Cancer. 2022. PMID: 36381271 Free PMC article.

6

Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1.

Amalina I, Bennett A, Whalley H, Perera D, McGrail JC, Tighe A, Procter DJ, Taylor SS. Amalina I, et al. Among authors: mcgrail jc. R Soc Open Sci. 2021 Dec 15;8(12):210854. doi: 10.1098/rsos.210854. eCollection 2021 Dec. R Soc Open Sci. 2021. PMID: 34925867 Free PMC article.

7

Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing.

McGrail JC, Tatum EM, O'Keefe RT. McGrail JC, et al. EMBO J. 2006 Aug 23;25(16):3813-22. doi: 10.1038/sj.emboj.7601258. Epub 2006 Aug 3. EMBO J. 2006. PMID: 16888626 Free PMC article.

8

The U1, U2 and U5 snRNAs crosslink to the 5' exon during yeast pre-mRNA splicing.

McGrail JC, O'Keefe RT. McGrail JC, et al. Nucleic Acids Res. 2008 Feb;36(3):814-25. doi: 10.1093/nar/gkm1098. Epub 2007 Dec 15. Nucleic Acids Res. 2008. PMID: 18084028 Free PMC article.

9

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing.

McGrail JC, Krause A, O'Keefe RT. McGrail JC, et al. Nucleic Acids Res. 2009 Jul;37(13):4205-17. doi: 10.1093/nar/gkp341. Epub 2009 May 12. Nucleic Acids Res. 2009. PMID: 19435883 Free PMC article.

10

The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing.

Hogg R, McGrail JC, O'Keefe RT. Hogg R, et al. Among authors: mcgrail jc. Biochem Soc Trans. 2010 Aug;38(4):1110-5. doi: 10.1042/BST0381110. Biochem Soc Trans. 2010. PMID: 20659013 Free PMC article. Review.

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