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Impact of Obefazimod on Viral Persistence, Inflammation, and Immune Activation in People With Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy.
Bernal S, Puertas MC, Morón-López S, Cranston RD, Urrea V, Dalmau J, Salgado M, Gálvez C, Erkizia I, McGowan I, Scherrer D, Revollo B, Sirera G, Santos JR, Clotet B, Paredes R, Martinez-Picado J. Bernal S, et al. Among authors: mcgowan i. J Infect Dis. 2023 Nov 2;228(9):1280-1291. doi: 10.1093/infdis/jiad251. J Infect Dis. 2023. PMID: 37395474 Free PMC article.
A germ-free humanized mouse model shows the contribution of resident microbiota to human-specific pathogen infection.
Wahl A, Yao W, Liao B, Chateau M, Richardson C, Ling L, Franks A, Senthil K, Doyon G, Li F, Frost J, Whitehurst CB, Pagano JS, Fletcher CA, Azcarate-Peril MA, Hudgens MG, Rogala AR, Tucker JD, McGowan I, Sartor RB, Garcia JV. Wahl A, et al. Among authors: mcgowan i. Nat Biotechnol. 2023 Aug 10:10.1038/s41587-023-01906-5. doi: 10.1038/s41587-023-01906-5. Online ahead of print. Nat Biotechnol. 2023. PMID: 37563299
Tenofovir Douche as HIV Preexposure Prophylaxis for Receptive Anal Intercourse: Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics (DREAM 01).
Weld ED, McGowan I, Anton P, Fuchs EJ, Ho K, Carballo-Dieguez A, Rohan LC, Giguere R, Brand R, Edick S, Bakshi RP, Parsons T, Manohar M, Seigel A, Engstrom J, Elliott J, Jacobson C, Bagia C, Wang L, Al-Khouja A, Hartman DJ, Bumpus NN, Spiegel HML, Marzinke MA, Hendrix CW. Weld ED, et al. Among authors: mcgowan i. J Infect Dis. 2024 Apr 12;229(4):1131-1140. doi: 10.1093/infdis/jiad535. J Infect Dis. 2024. PMID: 38019657 Clinical Trial.
Ex-vivo rectal tissue infection with HIV-1 to assess time to protection following oral preexposure prophylaxis with tenofovir disoproxil/emtricitabine.
Chawki S, Goldwirt L, Mouhebb ME, Gabassi A, Taouk M, Bichard I, Loze B, Amara A, Brand R, Siegel A, McGowan I, Costagliola D, Assoumou L, Molina JM, Delaugerre C; ANRS PREVENIR Study group. Chawki S, et al. Among authors: mcgowan i. AIDS. 2024 Mar 15;38(4):455-464. doi: 10.1097/QAD.0000000000003789. Epub 2023 Nov 22. AIDS. 2024. PMID: 37976073 Free PMC article.
The Association Between Heterosexual anal Intercourse and HIV Acquisition in Three Prospective Cohorts of Women.
Silhol R, Nordsletten A, Maheu-Giroux M, Elmes J, Staunton R, Owen B, Shacklett B, McGowan I, Feliciano KG, van der Straten A, Eller LA, Robb M, Marrazzo J, Dimitrov D, Boily MC. Silhol R, et al. Among authors: mcgowan i. AIDS Behav. 2023 Dec;27(12):4010-4021. doi: 10.1007/s10461-023-04115-y. Epub 2023 Jul 1. AIDS Behav. 2023. PMID: 37392271 Free PMC article.
A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4+ cell distribution in the human rectal mucosa.
Franzén Boger M, Benhach N, Hasselrot T, Brand RM, Rohan LC, Wang L, McGowan I, Edick S, Ho K, Meyn L, Matoba N, Palmer KE, Broliden K, Tjernlund A. Franzén Boger M, et al. Among authors: mcgowan i. Sci Rep. 2023 May 9;13(1):7547. doi: 10.1038/s41598-023-34107-w. Sci Rep. 2023. PMID: 37161022 Free PMC article.
Group early intervention eye movement desensitization and reprocessing therapy as a video-conference psychotherapy with frontline/emergency workers in response to the COVID-19 pandemic in the treatment of post-traumatic stress disorder and moral injury-An RCT study.
Farrell D, Moran J, Zat Z, Miller PW, Knibbs L, Papanikolopoulos P, Prattos T, McGowan I, McLaughlin D, Barron I, Mattheß C, Kiernan MD. Farrell D, et al. Among authors: mcgowan i. Front Psychol. 2023 Mar 23;14:1129912. doi: 10.3389/fpsyg.2023.1129912. eCollection 2023. Front Psychol. 2023. PMID: 37063579 Free PMC article.
Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial.
Bailón L, Llano A, Cedeño S, Escribà T, Rosás-Umbert M, Parera M, Casadellà M, Lopez M, Pérez F, Oriol-Tordera B, Ruiz-Riol M, Coll J, Perez F, Rivero À, Leselbaum AR, McGowan I, Sengupta D, Wee EG, Hanke T, Paredes R, Alarcón-Soto Y, Clotet B, Noguera-Julian M, Brander C, Molto J, Mothe B; AELIX002 Study Group. Bailón L, et al. Among authors: mcgowan i. Nat Med. 2022 Dec;28(12):2611-2621. doi: 10.1038/s41591-022-02060-2. Epub 2022 Oct 27. Nat Med. 2022. PMID: 36302893 Clinical Trial.
157 results