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Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models.
Tian M, McGovern K, Cheng HL, Waddicor P, Rieble L, Dao M, Chen Y, Kimble MT, Cantor E, Manfredonia N, Judson R, Chapdelaine-Williams A, Cain DW, Haynes BF, Alt FW. Tian M, et al. Among authors: mcgovern k. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7929-7940. doi: 10.1073/pnas.1921996117. Epub 2020 Mar 24. Proc Natl Acad Sci U S A. 2020. PMID: 32209668 Free PMC article.
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Saunders KO, Wiehe K, Tian M, Acharya P, Bradley T, Alam SM, Go EP, Scearce R, Sutherland L, Henderson R, Hsu AL, Borgnia MJ, Chen H, Lu X, Wu NR, Watts B, Jiang C, Easterhoff D, Cheng HL, McGovern K, Waddicor P, Chapdelaine-Williams A, Eaton A, Zhang J, Rountree W, Verkoczy L, Tomai M, Lewis MG, Desaire HR, Edwards RJ, Cain DW, Bonsignori M, Montefiori D, Alt FW, Haynes BF. Saunders KO, et al. Among authors: mcgovern k. Science. 2019 Dec 6;366(6470):eaay7199. doi: 10.1126/science.aay7199. Science. 2019. PMID: 31806786 Free PMC article.
An in vivo method for diversifying the functions of therapeutic antibodies.
Tian M, Cheng HL, Kimble MT, McGovern K, Waddicor P, Chen Y, Cantor E, Qiu M, Tuchel ME, Dao M, Alt FW. Tian M, et al. Among authors: mcgovern k. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2025596118. doi: 10.1073/pnas.2025596118. Proc Natl Acad Sci U S A. 2021. PMID: 33658386 Free PMC article.
183 results