McGovern JA - Search Results

1

Rational Design of Mouse Models for Cancer Research.

Landgraf M, McGovern JA, Friedl P, Hutmacher DW. Landgraf M, et al. Among authors: mcgovern ja. Trends Biotechnol. 2018 Mar;36(3):242-251. doi: 10.1016/j.tibtech.2017.12.001. Epub 2018 Jan 5. Trends Biotechnol. 2018. PMID: 29310843 Review.

2

Engineering a humanized bone organ model in mice to study bone metastases.

Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, Wunner FM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D, Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Lévesque JP, Dalton PD, Taubenberger AV, Hutmacher DW. Martine LC, et al. Among authors: mcgovern ja. Nat Protoc. 2017 Apr;12(4):639-663. doi: 10.1038/nprot.2017.002. Epub 2017 Mar 2. Nat Protoc. 2017. PMID: 28253234

3

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study.

Shafiee A, McGovern JA, Lahr CA, Meinert C, Moi D, Wagner F, Landgraf M, De-Juan-Pardo E, Mazzieri R, Hutmacher DW. Shafiee A, et al. Among authors: mcgovern ja. Int J Cancer. 2018 Sep 15;143(6):1470-1482. doi: 10.1002/ijc.31528. Epub 2018 May 7. Int J Cancer. 2018. PMID: 29659011 Free article.

4

Animal models for bone tissue engineering and modelling disease.

McGovern JA, Griffin M, Hutmacher DW. McGovern JA, et al. Dis Model Mech. 2018 Apr 23;11(4):dmm033084. doi: 10.1242/dmm.033084. Dis Model Mech. 2018. PMID: 29685995 Free PMC article. Review.

5

Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.

Wagner F, Holzapfel BM, McGovern JA, Shafiee A, Baldwin JG, Martine LC, Lahr CA, Wunner FM, Friis T, Bas O, Boxberg M, Prodinger PM, Shokoohmand A, Moi D, Mazzieri R, Loessner D, Hutmacher DW. Wagner F, et al. Among authors: mcgovern ja. Biomaterials. 2018 Jul;171:230-246. doi: 10.1016/j.biomaterials.2018.04.030. Epub 2018 Apr 16. Biomaterials. 2018. PMID: 29705656

6

Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contracture.

Poh PSP, Schmauss V, McGovern JA, Schmauss D, Chhaya MP, Foehr P, Seeger M, Ntziachristos V, Hutmacher DW, van Griensven M, Schantz JT, Balmayor ER. Poh PSP, et al. Among authors: mcgovern ja. Eur J Med Res. 2018 Jun 4;23(1):30. doi: 10.1186/s40001-018-0322-0. Eur J Med Res. 2018. PMID: 29866167 Free PMC article.

7

Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone.

McGovern JA, Shafiee A, Wagner F, Lahr CA, Landgraf M, Meinert C, Williams ED, Russell PJ, Clements JA, Loessner D, Holzapfel BM, Risbridger GP, Hutmacher DW. McGovern JA, et al. Cancers (Basel). 2018 Nov 13;10(11):438. doi: 10.3390/cancers10110438. Cancers (Basel). 2018. PMID: 30428629 Free PMC article.

8

A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma.

Wagner F, Holzapfel BM, Martine LC, McGovern J, Lahr CA, Boxberg M, Prodinger PM, Grässel S, Loessner D, Hutmacher DW. Wagner F, et al. Acta Biomater. 2019 Apr 15;89:372-381. doi: 10.1016/j.actbio.2019.02.051. Epub 2019 Mar 2. Acta Biomater. 2019. PMID: 30836200

9

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo.

Landgraf M, Lahr CA, Sanchez-Herrero A, Meinert C, Shokoohmand A, Pollock PM, Hutmacher DW, Shafiee A, McGovern JA. Landgraf M, et al. Among authors: mcgovern ja. Bone Res. 2019 Oct 21;7:31. doi: 10.1038/s41413-019-0072-9. eCollection 2019. Bone Res. 2019. PMID: 31646018 Free PMC article.

10

A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction.

Sparks DS, Saifzadeh S, Savi FM, Dlaska CE, Berner A, Henkel J, Reichert JC, Wullschleger M, Ren J, Cipitria A, McGovern JA, Steck R, Wagels M, Woodruff MA, Schuetz MA, Hutmacher DW. Sparks DS, et al. Among authors: mcgovern ja. Nat Protoc. 2020 Mar;15(3):877-924. doi: 10.1038/s41596-019-0271-2. Epub 2020 Feb 14. Nat Protoc. 2020. PMID: 32060491

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