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Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist.
Pickford P, Lucey M, Rujan RM, McGlone ER, Bitsi S, Ashford FB, Corrêa IR, Hodson DJ, Tomas A, Deganutti G, Reynolds CA, Owen BM, Tan TM, Minnion J, Jones B, Bloom SR. Pickford P, et al. Among authors: mcglone er. Mol Metab. 2021 Sep;51:101242. doi: 10.1016/j.molmet.2021.101242. Epub 2021 Apr 30. Mol Metab. 2021. PMID: 33933675 Free PMC article.
Bile acids and the metabolic syndrome.
McGlone ER, Bloom SR. McGlone ER, et al. Ann Clin Biochem. 2019 May;56(3):326-337. doi: 10.1177/0004563218817798. Epub 2019 Mar 4. Ann Clin Biochem. 2019. PMID: 30453753 Free article. Review.
Adjunctive liraglutide treatment in patients with persistent or recurrent type 2 diabetes after metabolic surgery (GRAVITAS): a randomised, double-blind, placebo-controlled trial.
Miras AD, Pérez-Pevida B, Aldhwayan M, Kamocka A, McGlone ER, Al-Najim W, Chahal H, Batterham RL, McGowan B, Khan O, Greener V, Ahmed AR, Petrie A, Scholtz S, Bloom SR, Tan TM. Miras AD, et al. Among authors: mcglone er. Lancet Diabetes Endocrinol. 2019 Jul;7(7):549-559. doi: 10.1016/S2213-8587(19)30157-3. Epub 2019 Jun 4. Lancet Diabetes Endocrinol. 2019. PMID: 31174993 Clinical Trial.
Candy cane revision after Roux-en-Y gastric bypass.
Kamocka A, McGlone ER, Pérez-Pevida B, Moorthy K, Hakky S, Tsironis C, Chahal H, Miras AD, Tan T, Purkayastha S, Ahmed AR. Kamocka A, et al. Among authors: mcglone er. Surg Endosc. 2020 May;34(5):2076-2081. doi: 10.1007/s00464-019-06988-4. Epub 2019 Aug 8. Surg Endosc. 2020. PMID: 31392513 Free PMC article.
Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.
Buenaventura T, Bitsi S, Laughlin WE, Burgoyne T, Lyu Z, Oqua AI, Norman H, McGlone ER, Klymchenko AS, Corrêa IR Jr, Walker A, Inoue A, Hanyaloglu A, Grimes J, Koszegi Z, Calebiro D, Rutter GA, Bloom SR, Jones B, Tomas A. Buenaventura T, et al. Among authors: mcglone er. PLoS Biol. 2019 Aug 20;17(8):e3000097. doi: 10.1371/journal.pbio.3000097. eCollection 2019 Aug. PLoS Biol. 2019. PMID: 31430273 Free PMC article.
Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
Jones B, McGlone ER, Fang Z, Pickford P, Corrêa IR Jr, Oishi A, Jockers R, Inoue A, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Tomas A, Bloom SR. Jones B, et al. Among authors: mcglone er. J Biol Chem. 2021 Jan-Jun;296:100133. doi: 10.1074/jbc.RA120.016334. Epub 2020 Dec 4. J Biol Chem. 2021. PMID: 33268378 Free PMC article.
Differential effects of bile acids on the postprandial secretion of gut hormones: a randomized crossover study.
McGlone ER, Malallah K, Cuenco J, Wewer Albrechtsen NJ, Holst JJ, Vincent RP, Ling C, Khan OA, Verma S, Ahmed AR, Walters JRF, Khoo B, Bloom SR, Tan TMM. McGlone ER, et al. Am J Physiol Endocrinol Metab. 2021 Apr 1;320(4):E671-E679. doi: 10.1152/ajpendo.00580.2020. Epub 2021 Jan 18. Am J Physiol Endocrinol Metab. 2021. PMID: 33459181 Free article. Clinical Trial.
57 results