McGinty RK - Search Results

1

Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.

Budziszewski GR, Zhao Y, Spangler CJ, Kedziora KM, Williams MR, Azzam DN, Skrajna A, Koyama Y, Cesmat AP, Simmons HC, Arteaga EC, Strauss JD, Kireev D, McGinty RK. Budziszewski GR, et al. Among authors: mcginty rk. Nucleic Acids Res. 2022 May 6;50(8):4355-4371. doi: 10.1093/nar/gkac198. Nucleic Acids Res. 2022. PMID: 35390161 Free PMC article.

2

Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.

Anderson CJ, Baird MR, Hsu A, Barbour EH, Koyama Y, Borgnia MJ, McGinty RK. Anderson CJ, et al. Among authors: mcginty rk. Cell Rep. 2019 Feb 12;26(7):1681-1690.e5. doi: 10.1016/j.celrep.2019.01.058. Cell Rep. 2019. PMID: 30759380 Free PMC article.

3

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding.

Skrajna A, Goldfarb D, Kedziora KM, Cousins EM, Grant GD, Spangler CJ, Barbour EH, Yan X, Hathaway NA, Brown NG, Cook JG, Major MB, McGinty RK. Skrajna A, et al. Among authors: mcginty rk. Nucleic Acids Res. 2020 Sep 25;48(17):9415-9432. doi: 10.1093/nar/gkaa544. Nucleic Acids Res. 2020. PMID: 32658293 Free PMC article.

4

Structural basis of nucleosome-dependent cGAS inhibition.

Boyer JA, Spangler CJ, Strauss JD, Cesmat AP, Liu P, McGinty RK, Zhang Q. Boyer JA, et al. Among authors: mcginty rk. Science. 2020 Oct 23;370(6515):450-454. doi: 10.1126/science.abd0609. Epub 2020 Sep 10. Science. 2020. PMID: 32913000 Free PMC article.

5

Principles of nucleosome recognition by chromatin factors and enzymes.

McGinty RK, Tan S. McGinty RK, et al. Curr Opin Struct Biol. 2021 Dec;71:16-26. doi: 10.1016/j.sbi.2021.05.006. Epub 2021 Jun 28. Curr Opin Struct Biol. 2021. PMID: 34198054 Free PMC article. Review.

6

A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex.

Waybright JM, Clinkscales SE, Barnash KD, Budziszewski GR, Rectenwald JM, Chiarella AM, Norris-Drouin JL, Cholensky SH, Pearce KH, Herring LE, McGinty RK, Hathaway NA, James LI. Waybright JM, et al. Among authors: mcginty rk. ACS Chem Biol. 2021 Sep 17;16(9):1721-1736. doi: 10.1021/acschembio.1c00429. Epub 2021 Aug 20. ACS Chem Biol. 2021. PMID: 34415726 Free PMC article.

7

DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding.

Spangler CJ, Yadav SP, Li D, Geil CN, Smith CB, Wang GG, Lee TH, McGinty RK. Spangler CJ, et al. Among authors: mcginty rk. Cell Rep. 2022 Feb 15;38(7):110369. doi: 10.1016/j.celrep.2022.110369. Cell Rep. 2022. PMID: 35172132 Free PMC article.

8

Time Resolved-Fluorescence Resonance Energy Transfer platform for quantitative nucleosome binding and footprinting.

Wesley NA, Skrajna A, Simmons HC, Budziszewski GR, Azzam DN, Cesmat AP, McGinty RK. Wesley NA, et al. Among authors: mcginty rk. Protein Sci. 2022 Jun;31(6):e4339. doi: 10.1002/pro.4339. Protein Sci. 2022. PMID: 35634775 Free PMC article.

9

Determination of Histone Methyltransferase Structures in Complex with the Nucleosome by Cryogenic Electron Microscopy.

Spangler CJ, McGinty RK. Spangler CJ, et al. Among authors: mcginty rk. Methods Mol Biol. 2022;2529:149-168. doi: 10.1007/978-1-0716-2481-4_8. Methods Mol Biol. 2022. PMID: 35733015 Free PMC article.

10

The Effects of Histone H2B Ubiquitylations on the Nucleosome Structure and Internucleosomal Interactions.

Sengupta B, Huynh M, Smith CB, McGinty RK, Krajewski W, Lee TH. Sengupta B, et al. Among authors: mcginty rk. Biochemistry. 2022 Oct 18;61(20):2198-2205. doi: 10.1021/acs.biochem.2c00422. Epub 2022 Sep 16. Biochemistry. 2022. PMID: 36112542 Free PMC article.

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