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Use of a gene expression signature to identify trimetazidine for repurposing to treat bipolar depression.
Bortolasci CC, Kidnapillai S, Spolding B, Truong TTT, Connor T, Swinton C, Panizzutti B, Liu ZSJ, Sanigorski A, Dean OM, Crowley T, Richardson M, Bozaoglu K, Vlahos K, Cowdery S, Watmuff B, Steyn SF, Wolmarans W, Engelbrecht BJ, Perry C, Drummond K, Pang T, Jamain S, Gray L, McGee SL, Harvey BH, Kim JH, Leboyer M, Berk M, Walder K. Bortolasci CC, et al. Among authors: mcgee sl. Bipolar Disord. 2023 Dec;25(8):661-670. doi: 10.1111/bdi.13319. Epub 2023 Mar 23. Bipolar Disord. 2023. PMID: 36890661 Free PMC article.
Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo.
Konstantopoulos N, Molero JC, McGee SL, Spolding B, Connor T, de Vries M, Wanyonyi S, Fahey R, Morrison S, Swinton C, Jones S, Cooper A, Garcia-Guerra L, Foletta VC, Krippner G, Andrikopoulos S, Walder KR. Konstantopoulos N, et al. Among authors: mcgee sl. Diabetes. 2012 Aug;61(8):2146-54. doi: 10.2337/db11-0578. Epub 2012 May 14. Diabetes. 2012. PMID: 22586591 Free PMC article.
Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.
Gaur V, Connor T, Sanigorski A, Martin SD, Bruce CR, Henstridge DC, Bond ST, McEwen KA, Kerr-Bayles L, Ashton TD, Fleming C, Wu M, Pike Winer LS, Chen D, Hudson GM, Schwabe JWR, Baar K, Febbraio MA, Gregorevic P, Pfeffer FM, Walder KR, Hargreaves M, McGee SL. Gaur V, et al. Among authors: mcgee sl. Cell Rep. 2016 Sep 13;16(11):2802-2810. doi: 10.1016/j.celrep.2016.08.005. Cell Rep. 2016. PMID: 27626651 Free article.
125 results