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Venous-plexus-associated lymphoid hubs support meningeal humoral immunity.
Fitzpatrick Z, Ghabdan Zanluqui N, Rosenblum JS, Tuong ZK, Lee CYC, Chandrashekhar V, Negro-Demontel ML, Stewart AP, Posner DA, Buckley M, Allinson KSJ, Mastorakos P, Chittiboina P, Maric D, Donahue D, Helmy A, Tajsic T, Ferdinand JR, Portet A, Peñalver A, Gillman E, Zhuang Z, Clatworthy MR, McGavern DB. Fitzpatrick Z, et al. Among authors: mcgavern db. Nature. 2024 Apr;628(8008):612-619. doi: 10.1038/s41586-024-07202-9. Epub 2024 Mar 20. Nature. 2024. PMID: 38509366
Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. Gaud G, et al. Among authors: mcgavern db. Nat Immunol. 2024 Mar;25(3):579. doi: 10.1038/s41590-023-01725-5. Nat Immunol. 2024. PMID: 38057618 No abstract available.
CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. Gaud G, et al. Among authors: mcgavern db. Nat Immunol. 2023 Dec;24(12):2121-2134. doi: 10.1038/s41590-023-01663-2. Epub 2023 Nov 9. Nat Immunol. 2023. PMID: 37945821
A protocol for visualization of murine in situ neurovascular interfaces.
Dang DD, Chandrashekhar V, Chandrashekhar V, Ghabdanzanluqui N, Knutsen RH, Nazari MA, Nimmagadda L, Donahue DR, McGavern DB, Kozel BA, Heiss JD, Pacak K, Zhuang Z, Rosenblum JS. Dang DD, et al. Among authors: mcgavern db. STAR Protoc. 2023 Sep 15;4(3):102367. doi: 10.1016/j.xpro.2023.102367. Epub 2023 Jun 19. STAR Protoc. 2023. PMID: 37339049 Free PMC article.
Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss.
Fernando N, Gopalakrishnan J, Behensky A, Reich L, Liu C, Bass V, Bono M, Montgomery W, De Pace R, Mattapallil M, Nagarajan V, Brooks S, Maric D, Caspi RR, McGavern DB, Shih HY. Fernando N, et al. Among authors: mcgavern db. bioRxiv [Preprint]. 2023 Mar 22:2023.03.18.533293. doi: 10.1101/2023.03.18.533293. bioRxiv. 2023. PMID: 37090642 Free PMC article. Preprint.
Bacterial meningitis hits an immunosuppressive nerve.
Zanluqui NG, McGavern DB. Zanluqui NG, et al. Among authors: mcgavern db. Nature. 2023 Mar;615(7952):396-397. doi: 10.1038/d41586-023-00540-0. Nature. 2023. PMID: 36859668 No abstract available.
Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury.
Mason H, Rai G, Kozyr A, De Jonge N, Gliniewicz E, Berg LJ, Wald G, Dorrier C, Henderson MJ, Zakharov A, Dyson T, Audley J, Pettinato AM, Padilha EC, Shah P, Xu X, Leto TL, Simeonov A, Zarember KA, McGavern DB, Gallin JI. Mason H, et al. Among authors: mcgavern db. Redox Biol. 2023 Apr;60:102611. doi: 10.1016/j.redox.2023.102611. Epub 2023 Jan 18. Redox Biol. 2023. PMID: 36709665 Free PMC article.
Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function.
Zhang Y, Bailey JT, Xu E, Singh K, Lavaert M, Link VM, D'Souza S, Hafiz A, Cao J, Cao G, Sant'Angelo DB, Sun W, Belkaid Y, Bhandoola A, McGavern DB, Yang Q. Zhang Y, et al. Among authors: mcgavern db. Nat Immunol. 2022 Dec;23(12):1714-1725. doi: 10.1038/s41590-022-01349-1. Epub 2022 Nov 21. Nat Immunol. 2022. PMID: 36411380 Free PMC article.
136 results