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A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
Zeller J, Cheung Tung Shing KS, Nero TL, McFadyen JD, Krippner G, Bogner B, Kreuzaler S, Kiefer J, Horner VK, Braig D, Danish H, Baratchi S, Fricke M, Wang X, Kather MG, Kammerer B, Woollard KJ, Sharma P, Morton CJ, Pietersz G, Parker MW, Peter K, Eisenhardt SU. Zeller J, et al. Among authors: mcfadyen jd. EMBO Mol Med. 2023 Jan 11;15(1):e16236. doi: 10.15252/emmm.202216236. Epub 2022 Dec 5. EMBO Mol Med. 2023. PMID: 36468184 Free PMC article.
Platelets are not just for clots.
McFadyen JD, Kaplan ZS. McFadyen JD, et al. Transfus Med Rev. 2015 Apr;29(2):110-9. doi: 10.1016/j.tmrv.2014.11.006. Epub 2015 Jan 12. Transfus Med Rev. 2015. PMID: 25680870 Review.
The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.
Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP. Mountford JK, et al. Among authors: mcfadyen jd. Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535. Nat Commun. 2015. PMID: 25779105 Free article.
77 results