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Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease.
Clotet-Freixas S, Zaslaver O, Kotlyar M, Pastrello C, Quaile AT, McEvoy CM, Saha AD, Farkona S, Boshart A, Zorcic K, Neupane S, Manion K, Allen M, Chan M, Chen X, Arnold AP, Sekula P, Steinbrenner I, Köttgen A, Dart AB, Wicklow B, McGavock JM, Blydt-Hansen TD, Barrios C, Riera M, Soler MJ, Isenbrandt A, Lamontagne-Proulx J, Pradeloux S, Coulombe K, Soulet D, Rajasekar S, Zhang B, John R, Mehrotra A, Gehring A, Puhka M, Jurisica I, Woo M, Scholey JW, Röst H, Konvalinka A. Clotet-Freixas S, et al. Among authors: mcevoy cm. Sci Transl Med. 2024 Mar 6;16(737):eabm2090. doi: 10.1126/scitranslmed.abm2090. Epub 2024 Mar 6. Sci Transl Med. 2024. PMID: 38446901
Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study.
Clotet-Freixas S, McEvoy CM, Batruch I, Pastrello C, Kotlyar M, Van JAD, Arambewela M, Boshart A, Farkona S, Niu Y, Li Y, Famure O, Bozovic A, Kulasingam V, Chen P, Kim SJ, Chan E, Moshkelgosha S, Rahman SA, Das J, Martinu T, Juvet S, Jurisica I, Chruscinski A, John R, Konvalinka A. Clotet-Freixas S, et al. Among authors: mcevoy cm. J Am Soc Nephrol. 2020 Nov;31(11):2705-2724. doi: 10.1681/ASN.2020030286. Epub 2020 Sep 8. J Am Soc Nephrol. 2020. PMID: 32900843 Free PMC article.
Normothermic Ex-vivo Kidney Perfusion in a Porcine Auto-Transplantation Model Preserves the Expression of Key Mitochondrial Proteins: An Unbiased Proteomics Analysis.
McEvoy CM, Clotet-Freixas S, Tokar T, Pastrello C, Reid S, Batruch I, RaoPeters AAE, Kaths JM, Urbanellis P, Farkona S, Van JAD, Urquhart BL, John R, Jurisica I, Robinson LA, Selzner M, Konvalinka A. McEvoy CM, et al. Mol Cell Proteomics. 2021;20:100101. doi: 10.1016/j.mcpro.2021.100101. Epub 2021 May 23. Mol Cell Proteomics. 2021. PMID: 34033948 Free PMC article.
Increased Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B in Patients With Kidney Allograft Antibody-mediated Rejection.
Clotet-Freixas S, Kotlyar M, McEvoy CM, Pastrello C, Rodríguez-Ramírez S, Farkona S, Cardinal H, Dieudé M, Hébert MJ, Li Y, Famure O, Chen P, Kim SJ, Chan E, Jurisica I, John R, Chruscinski A, Konvalinka A. Clotet-Freixas S, et al. Among authors: mcevoy cm. Transplant Direct. 2021 Sep 20;7(10):e768. doi: 10.1097/TXD.0000000000001215. eCollection 2021 Oct. Transplant Direct. 2021. PMID: 34557585 Free PMC article.
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
McEvoy CM, Murphy JM, Zhang L, Clotet-Freixas S, Mathews JA, An J, Karimzadeh M, Pouyabahar D, Su S, Zaslaver O, Röst H, Arambewela R, Liu LY, Zhang S, Lawson KA, Finelli A, Wang B, MacParland SA, Bader GD, Konvalinka A, Crome SQ. McEvoy CM, et al. Nat Commun. 2022 Dec 10;13(1):7634. doi: 10.1038/s41467-022-35297-z. Nat Commun. 2022. PMID: 36496458 Free PMC article.
Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes.
Urbanellis P, McEvoy CM, Škrtić M, Kaths JM, Kollmann D, Linares I, Ganesh S, Oquendo F, Sharma M, Mazilescu L, Goto T, Noguchi Y, John R, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Selzner M, Robinson LA. Urbanellis P, et al. Among authors: mcevoy cm. Transplant Direct. 2021 Jul 8;7(8):e719. doi: 10.1097/TXD.0000000000001157. eCollection 2021 Aug. Transplant Direct. 2021. PMID: 34258386 Free PMC article.
Evaluation of a gene expression biomarker to identify operationally tolerant liver transplant recipients: the LITMUS trial.
Chruscinski A, Rojas-Luengas V, Moshkelgosha S, Issachar A, Luo J, Yowanto H, Lilly L, Smith R, Renner E, Zhang J, Epstein M, Grant D, McEvoy CM, Konvalinka A, Humar A, Adeyi O, Fischer S, Volmer FH, Taubert R, Jaeckel E, Juvet S, Selzner N, Levy GA. Chruscinski A, et al. Among authors: mcevoy cm. Clin Exp Immunol. 2022 Jan 28;207(1):123-139. doi: 10.1093/cei/uxab011. Clin Exp Immunol. 2022. PMID: 35020854 Free PMC article. Clinical Trial.
NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling.
Zhang T, He X, Caldwell L, Goru SK, Ulloa Severino L, Tolosa MF, Misra PS, McEvoy CM, Christova T, Liu Y, Atin C, Zhang J, Hu C, Vukosa N, Chen X, Krizova A, Kirpalani A, Gregorieff A, Ni R, Chan K, Gill MK, Attisano L, Wrana JL, Yuen DA. Zhang T, et al. Among authors: mcevoy cm. Sci Transl Med. 2022 Mar 23;14(637):eaaz4028. doi: 10.1126/scitranslmed.aaz4028. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320001
Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1.
Brennan EP, Nolan KA, Börgeson E, Gough OS, McEvoy CM, Docherty NG, Higgins DF, Murphy M, Sadlier DM, Ali-Shah ST, Guiry PJ, Savage DA, Maxwell AP, Martin F, Godson C; GENIE Consortium. Brennan EP, et al. Among authors: mcevoy cm. J Am Soc Nephrol. 2013 Mar;24(4):627-37. doi: 10.1681/ASN.2012060550. Epub 2013 Mar 21. J Am Soc Nephrol. 2013. PMID: 23520204 Free PMC article.
17 results