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A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.
Wang B, Liu Y, Huang L, Chen J, Li JJ, Wang R, Kim E, Chen Y, Justicia C, Sakata K, Chen H, Planas A, Ostrom RS, Li W, Yang G, McDonald MP, Chen R, Heck DH, Liao FF. Wang B, et al. Among authors: mcdonald mp. Mol Psychiatry. 2017 Jul;22(7):990-1001. doi: 10.1038/mp.2016.104. Epub 2016 Jul 26. Mol Psychiatry. 2017. PMID: 27457810 Free PMC article.
Thioredoxin interacting protein regulates age-associated neuroinflammation.
Ismael S, Nasoohi S, Li L, Aslam KS, Khan MM, El-Remessy AB, McDonald MP, Liao FF, Ishrat T. Ismael S, et al. Among authors: mcdonald mp. Neurobiol Dis. 2021 Aug;156:105399. doi: 10.1016/j.nbd.2021.105399. Epub 2021 May 21. Neurobiol Dis. 2021. PMID: 34029695 Free PMC article.
86 results